We're opening a new position in the field of flash photolysis of organic molecules. We require a skilled and experienced person with many years of experience in the area of flash photolysis technique with emphasis to its use in study of triplet states of organic substances. Fluent English is a must. We offer a job in an international team of young scientists.

Ph.D. position in organic chemistry, Prague, Czech Republic

Description:
A Ph.D position in organic chemistry is offered at the Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic in Prague. The project deals with the development of new domino processes and their application in the total synthesis of natural products.

Requirements:
The applicant should have an M.Sc. or equivalent degree in organic chemistry, a very good theoretical and practical background in organic synthesis and an expertise in structure elucidation of organic compounds. Will be motivated and have good oral and written English communication skills.

Salary: Annual salary 12.000 USD

Additional Info:
The applicant will work in an excellent European institute with state of the art facilities in an international group of Ph.D. students and postdocs. Prague offers a stimulating atmosphere to accomplish the goals and is an excellent place to live.

Start date: Position is available immediately.

How to apply:
Please send your CV, graduation certificates and transcript of records to: Dr. Ullrich Jahn, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 16610 Prague 6, Czech Republic; Tel. +420-220183219; ✉: jahn@uochb.cas.cz.

Postdoctoral position in Immunology: Prague, Czech Republic

We are seeking a highly motivated and creative scientist with expertise in immunology to support our internal program focused on the identification of novel STING/TMEM173 ligands.

Job Description:
Our group is involved in biological characterization of novel STING/TMEM173 agonists prepared by our Medicinal Chemistry Department. The activation of this pattern recognition receptor results in the stimulation of host innate responses, and it is believed that STING represents a good target for drug discovery efforts aiming to treat chronic hepatitis B or cancer. The successful candidate will be a member of a multidisciplinary team and be responsible for conducting key immunological studies. He or she will be performing multiplex ELISA assays, and study the effect of agonists on different population of immune cells in vitro and in vivo, and evaluate STING-dependent signaling in murine and human cells. The candidate will also have an opportunity to perform research focused on expanding our understanding of STING biology. Located in the stunning city of Prague, our research facilities comprise a state-of-the-art instrumentation portfolio.

Requirements:
Applicant must have Ph.D. in immunology. An extensive knowledge of standard immunological techniques including isolation and culturing of primary cells, lymphoproliferative assays, cell-based functional assays, and immune phenotyping by multi-parameter FACS analysis is required. Experience working with infectious materials is advantageous, but not required. Good oral and written communication skills in English are required as well as the ability to work independently. Position is for 24 months starting from October 1st 2016 with possible extension.

How to apply:
Please submit cover letter, CV, and contact information for 2-3 references combined into one PDF file by e-mail to: helena.kaiserova@uochb.cas.cz

Contacts:
Dr. Helena Mertlíková Kaiserová
Institute of Organic Chemistry and Biochemistry CAS, v.v.i.
Flemingovo n. 542/2, 166 10 Prague 6, Czech Republic
✉: helena.kaiserova@uochb.cas.cz

Postdoctoral Research Associate - Dr. Michael J. Bojdys Group

Two postdoctoral positions in design, processing and applications of layered functional materials "beyond graphene" (BEGMAT).
[ Detail info here ]

Ph.D. Studentship - Dr. Michael J. Bojdys Group

Three Ph.D. positions in high throughput discovery of layered functional materials "beyond graphene" (BEGMAT).
[ Detail info here ]

Postdoctoral position in Biochemistry/Structural Biology: Prague, Czech Republic

We are seeking a highly motivated individual who is willing to accept the challenge of cutting edge research at the interface biochemistry/structural biology of G-quadruplexes.

Job Description: This project is focused mainly at c-myc G-quadruplex and will also involve evaluation of small molecule ligands using techniques of biochemistry/molecular biology. Successful applicant for this postdoc position will be an outstanding self-driven person who will primarily explore the crystallizations of promoter G-quadruplexes with small molecule ligands. The aim is to elucidate molecular details of their interaction. Innovative crystallization approaches will be pursued. Located in the stunning city of Prague, our research facilities comprise a state-of-the-art instrumentation portfolio.

Requirements: Applicant must have Ph.D. in biology, biochemistry or a closely related discipline. The candidates must be a first author on at least 2-3 publications. This position requires prior experience in biochemistry and structural biology techniques. Excellent oral and written communication skills in English are required as well as the ability to conduct independent scientific investigations. Position is for one year with possible extension.

How to apply: Please submit cover letter, CV, and contact information for 2-3 references combined into one PDF file by e-mail to: teply@uochb.cas.cz and rezacova@uochb.cas.cz

Contacts:
Filip Teplý, Ph.D. and Pavlína Řezáčová, Ph.D.
Institute of Organic Chemistry and Biochemistry CAS, v.v.i.
Flemingovo nám. 542/2
166 10 Prague 6
Czech Republic
✉: teply@uochb.cas.cz / rezacova@uochb.cas.cz