Organic Chemistry

Tutor	Mgr. Radim Nencka, Ph.D.
Team	Radim Nencka
Topic	Novel heterocyclic derivatives as lipid and protein kinase inhibitors
Faculty	FPBT VŠCHT, PřF UK
Abstract	Lipid and protein kinases represent important molecular targets for advanced therapeutics with a wide range of indications. The project will be focused on rational design and synthesis of novel inhibitors of phosphatidylinositol 4-kinase, which may serve as potential therapeutics against various types of solid tumors, viral infections or neurodegenerative diseases.