Ing. Martin Klečka, Ph.D.

e-mail: klecka@uochb.cas.cz
phone: +420 221951331


Born 30. 01. 1982 in Praha (Czech Republic).

Scientific CV:
2001-2007 undergraduate study, Prague Institute of Chemical Technology, M. S. degree - specialization organic chemistry (supervisor Prof. D. Dvořák)
2004-2005 study abroad University of Glasgow, Scotland, United Kingdom (supervisor prof. P. Kočovský)
2007-2008 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)
2009-2011 research and development, AMGEN CZ
04/2011-2016 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Prof. Dr. M. Hocek)
since 2016 Postdoctoral stay, University if Southern Denmark (supervisor Ass. Prof. Kira Astakhova)

List of publications:

8.	Klečka, M.; Poštová Slavětínská, L.; Hocek, M.: "Modification of Pyrrolo[2,3-d]pyrimidines by C–H Borylation Followed by Cross-Coupling or Other Transformations: Synthesis of 6,8-Disubstituted 7-Deazapurine Bases" Eur. J. Org. Chem. 2015, 36, 7943 – 7961.
7.	Klečka, M.; Slavětínská, L.; Tloušťová, E.; Džubák, P.; Hajdúch, M.; Hocek, M.: "Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides" Med. Chem. Commun. 2015, 6, 576–580.
6.	Sabat, N.; Klečka, M.; Slavětínská, L.; Klepetářová, B.; Hocek, M.: "Direct C–H amination and C–H chloroamination of 7-deazapurines" RSC Adv. 2014, 4, 62140 – 62143.
5.	Krömer, M.; Klečka, M.; Slavětínská, L.; Klepetářová, B.; Hocek, M.: "Chemoselective synthesis of 4,5-diarylpyrrolo[2,3-d]pyrimidines (6,7-diaryl-7-deazapurines) by consecutive Suzuki and Liebeskind-Srogl cross-couplings" Eur. J. Org. Chem. 2014, 32, 7203–7210.
4.	Klečka, M.; Pohl, R.; Čejka, J.; Hocek, M.: "Direct C–H sulfenylation of purines and deazapurines" Org. Biomol. Chem. 2013, 11, 5189-5193.
3.	Klečka, M.; Křováček, M.; Tobrman, T.; Dvořák, D.: "Synthesis of (E)-6-alkenylpurines via Pd-catalyzed stannation/protodestannation tandem process of alkynylpurines" Collect. Czech. Chem. Commun. 2010, 75, 313-332.
2.	Klečka, M.; Pohl, R.; Klepetářová, B.; Hocek, M.: "Direct C–H borylation and C–H arylation of pyrrolo[2,3-d]pyrimidines: synthesis of 6,8-disubstituted 7-deazapurines" Org. Biomol. Chem. 2009, 7, 866-868.
1.	Klečka, M.; Tobrman, T.; Dvořák, D.: "Cu(I)-Catalyzed Coupling of (9-Benzylpurin-6-yl)magnesium Chloride with Allyl Halides: an Approach to 6-Allylpurine Derivates" Collect. Czech. Chem. Commun. 2006, 71, 1221–1228.