INSTITUTE OF PHYSIOLOGY CAS

Physiological and molecular changes during the progression cardiac failure The discovered parameters could present new prognostic markers of sudden cardiac death in heart failure patients.

A new model of obsessive-compulsive disorder (OCD) It is possible to induce states similar to obsessive-compulsive disorder even in rats. These models are used for testing of new therapeutic interventions. Read how animal models help medicine.

Structural motifs within the TRPA1 receptor contribute to detection of painful stimuli Acute pain is a normal reaction of the somatosensory system to noxious stimulation which serves a protective function and is the first symptom of disease, especially of inflammatory origin. In its chronic form, pain is maladaptive and has a significant impact on quality of life. The scientists from the Department of Cellular Neurophysiology investigate the function of a distinct group of proteins involved in the mechanisms of acute and chronic pain.