Publikace

2016


204. Matyašovský J., Perlíková P., Malnuit V., Pohl R., Hocek M.:
2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove.
Angewandte Chemie International Edition 55: 15856-15859, 2016.

 
203. Slavíčková M., Pohl R., Hocek M.:
Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2'-Deoxyadenosine, dATP and DNA.
Journal of Organic Chemistry 81: 11115-11125, 2016.

 
202. Cahová H., Panattoni A., Kielkowski P., Fanfrlík J., Hocek M.:
5-Substituted Pyrimidine and 7-Substituted 7-Deazapurine dNTPs as Substrates for DNA Polymerases in Competitive Primer Extension in the Presence of Natural dNTPs.
ACS Chemical Biology 11: 3165-3171, 2016.

 
201. Botha F., Slavíčková M., Pohl R., Hocek M.:
Copper-mediated arylsulfanylations and arylselanylations of pyrimidine or 7-deazapurine nucleosides and nucleotides.
Organic & Biomolecular Chemistry 14: 10018-10022, 2016.

 
200. Sabat N., Poštová Slavětínská L., Klepetářová B., Hocek M.:
C–H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7- and 9-Deazapurine-8-phosphonate Derivatives.
Journal of Organic Chemistry 81: 9507-9514, 2016.

 
199. Olszewska A., Pohl R., Brázdová M., Fojta M., Hocek M.:
Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins.
Bioconjugate Chemistry 27: 2089-2094, 2016.

 
198. Bosáková A., Perlíková P., Tichý M., Pohl R., Hocek M.:
6-Aryl-4-amino-pyrimido[4,5-b]indole 2'-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study.
Bioorganic & Medicinal Chemistry 24: 4528-4535, 2016.

 
197. Dziuba D., Pospíšil P., Matyašovský J., Brynda J., Nachtigallová D., Rulíšek L., Pohl R., Hof M., Hocek M.:
Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions.
Chemical Science 7: 5775-5785, 2016.

 
196. Danhel A., Trošanová Z., Balintová J., Havran L., Hocek M., Barek J., Fojta M.:
Voltammetric analysis of 5-(4-Azidophenyl)-2'-deoxycytidine nucleoside and azidophenyl-labelled single- and double-stranded DNAs.
Electrochimica Acta 215: 72-83, 2016.

 
195. Perlíková P., Rylová G., Nauš P., Elbert T., Tloušťová E., Bourderioux A., Poštová Slavětínská L., Motyka K., Doležal D., Znojek P., Nová A., Harvanová M., Džubák P., Šiller M., Hlaváč J., Hajdúch M., Hocek M.:
7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action.
Molecular Cancer Therapy 15: 922-937, 2016.

 
194. Raindlová V., Janoušková M., Slavíčková M., Perlíková P., Boháčová S., Milisavljevič N., Šanderová H., Benda M., Barvík I., Krásný L., Hocek M.:
Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases.
Nucleic Acids Research 44: 3000-3012, 2016.

 
193. Daďová J., Cahová H., Hocek M.:
Polymerase Synthesis of Base-Modified DNA.
K. Nakatani, Y. Tor (eds.), Modified Nucleic Acids, Nucleic Acids and Molecular Biology Series Vol. 31: 123-144, Springer 2016.

 
192. Sabat N., Nauš P., Matyašovský J., Dziuba D., Poštová Slavetínská L., Hocek M.:
Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurineBases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions.
Synthesis 48: 1029-1045, 2016.

 
191. Kielkowski P., Cahová H., Pohl R., Hocek M.:
Flexible double-headed cytosine-linked 2'-deoxycytidine nucleotides. Synthesis, polymerase incorporation to DNA and interaction with DNA methyltransferases.
Bioorganic & Medicinal Chemistry 24: 1268-1276, 2016.

 
190. Dziuba D., Jurkiewicz P., Cebecauer M., Hof M., Hocek M.:
A Rotational BODIPY Nucleotide: An Environment-Sensitive Fluorescence-Lifetime Probe for DNA Interactions and Applications in Live-Cell Microscopy.
Angewandte Chemie International Edition 55: 174-178, 2016.

 
189. Güixens-Gallardo P., Hocek M., Perlíková P.:
Inhibition of non-templated nucleotide addition by DNA polymerases in primer extension using twisted intercalating nucleic acid modified templates.
Bioorganic & Medicinal Chemistry Letters 26: 288-291, 2016.


2015


188. Tokarenko A., Poštová Slavětínská L., Klepetářová B., Hocek M.:
Synthesis of Benzene and Pyridine 2'-C-Methyl-C-ribonucleosides and -nucleotides.
European Journal of Organic Chemistry 36: 7962-7983, 2015.

 
187. Klečka M., Poštová Slavětínská L., Hocek M.:
Modification of Pyrrolo[2,3-d]pyrimidines by C–H Borylation Followed by Cross-Coupling or Other Transformations: Synthesis of 6,8-Disubstituted 7-Deazapurine Bases.
European Journal of Organic Chemistry 36: 7943-7961, 2015.

 
186. Nauš P., Caletková O., Perlíková P., Poštová Slavětínská L., Tloušťová E., Hodek J., Weber J., Džubák P., Hajdúch M., Hocek M.:
Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides.
Bioorganic & Medicinal Chemistry 23: 7422-7438, 2015.

 
185. Sabat N., Poštová Slavětínská L., Hocek M.:
Ir-catalyzed C–H silylations of phenyldeazapurines.
Tetrahedron Letters 49: 6860-6862, 2015.

 
184. Olszewska A., Daďová J., Mačková M., Hocek M.:
Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases.
Bioorganic & Medicinal Chemistry 21: 6885-6890, 2015.

 
183. Daďová J., Vrábel M., Adámik M., Brázdová M., Pohl R., Fojta M., Hocek M.:
Azidopropylvinylsulfonamide as a New Bifunctional Click Reagent for Bioorthogonal Conjugations: Application for DNA–Protein Cross-Linking.
Chemistry A European Journal 21: 16091-16102, 2015.

 
182. Mačková M., Boháčová S., Perlíková P., Poštová Slavětínská L., Hocek M.:
Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7-Substituted 7-Deazaguanine.
ChemBioChem 16: 2225-2236, 2015.

 
181. Downey A. M., Richter C., Pohl R., Mahrwald R., Hocek M.:
Direct One-Pot Synthesis of Nucleosides from Unprotected or 5-O-Monoprotected D-Ribose.
Organic Letters 17: 4604-4607, 2015.

 
180. Malnuit V., Poštová Slavětínská L., Nauš P., Džubák P., Hajdúch M., Stolaříková J., Snášel J., Pichová I., Hocek M.:
2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.
ChemMedChem 10: 1079-1093, 2015.

 
179. Klečka M., Slavětínská L., Tloušťová E., Džubák P., Hajdúch M., Hocek M.:
Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides.
MedChemComm 6: 576-580, 2015.

 
178. Dziuba D., Pohl R., Hocek M.:
Polymerase synthesis of DNA labelled with benzylidene cyanoacetamide-based fluorescent molecular rotors: fluorescent light-up probes for DNA-binding proteins.
Chemical Communications 51: 4880-4882, 2015.

 
177. Ménová P., Dziuba D., Güixens-Gallardo P., Jurkiewicz P., Hof M., Hocek M.:
Fluorescence Quenching in Oligonucleotides Containing 7-Substituted 7-Deazaguanine Bases Prepared by the Nicking Enzyme Amplification Reaction.
Bioconjugate Chemistry 26: 361-366, 2015.

 
176. Balintová J., Špaček J., Pohl R., Brázdová M., Havran L., Fojta M., Hocek M.:
Azidophenyl as a click-transformable redox label of DNA suitable for electrochemical detection of DNA-protein interactions.
Chemical Science 6: 575-587, 2015.


2014


175. Simonova A., Balintová J., Pohl R., Havran L., Fojta M., Hocek M.:
Methoxyphenol and dihydrobenzofuran as new oxidizable labels for electrochemical detection of DNA.
ChemPlusChem 79: 1703-1712, 2014.
 
174. Dziuba D., Pohl R., Hocek M.:
Bodipy-labelled nucleoside triphosphates for polymerase synthesis of fluorescent DNA.
Bioconjugate Chemistry 25: 1984-1995, 2014.
 
173. Sabat N., Klečka M., Slavětínská L., Klepetářová B., Hocek M.:
Direct C–H amination and C–H chloroamination of 7-deazapurines.
RSC Advances 4: 62140-62143, 2014.
 
172. Hocek M.:
Synthesis of Base-Modified 2'-Deoxyribonucleoside Triphosphates and Their Use in Enzymatic Synthesis of Modified DNA for Applications in Bioanalysis and Chemical Biology.
Journal of Organic Chemistry 79: 9914-9921, 2014.
 
171. Krömer M., Klečka M., Slavětínská L., Klepetářová B., Hocek M.:
Chemoselective synthesis of 4,5-diarylpyrrolo[2,3-d]pyrimidines (6,7-diaryl-7-deazapurines) by consecutive Suzuki and Liebeskind-Srogl cross-couplings.
European Journal of Organic Chemistry 32: 7203-7210, 2014.
 
170. Snášel J., Nauš P., Dostál J., Hnízda A., Fanfrlík J., Brynda J., Bourderioux A., Dušek M., Dvořáková H., Stolaříková J., Zábranská H., Pohl R., Konečný P., Džubák P., Votruba I., Hajdúch M., Řezáčová P., Veverka V., Hocek M., Pichová I.:
Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(het)aryl-7-deazaadenine ribonucleosides.
Journal of Medicinal Chemistry 57: 8268-8279, 2014.
 
169. Mačková M., Pohl R., Hocek M.:
Polymerase synthesis of DNA bearing vinyl groups in major groove and their cleavage by restriction endonucleases.
ChemiBioChem 15: 2306-2312, 2014.
 
168. Dhami K., Malyshev D. A., Ordoukhanian P., Kubelka T., Hocek M., Romesberg F. E.:
Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet.
Nucleic Acids Research 42: 10325-10244, 2014.
 
167. Kielkowski P., Fanfrlík J., Hocek M.:
7-Aryl-7-deazaadenine 2'-Deoxyribonucleoside Triphosphates (dNTPs): Better Substrates for DNA Polymerases than dATP in Competitive Incorporations.
Agewandte Chemie Interantional Edition 53: 7552-7555, 2014.
 
166. Vaníková Z., Hocek M.:
Polymerase Synthesis of Photocaged DNA Resistant against Cleavage by Restriction Endonucleases.
Agewandte Chemie Interantional Edition 53: 6734-6737, 2014.
 
165. Hocek M.:
Preparation of Base-Modified DNA by Enzymatic Incorporation of Modified Nucleoside Triphosphates (in Czech).
Chemické Listy 108: 320-325, 2014.
 
164. Čerňová M., Pohl R., Klepetářová B., Hocek M.:
C-H Trifluormethylations of 1,3-dimethyluracil and reactivity of the products in C-H arylations.
Heterocycles 89: 1159-1171, 2014.
 
163. Danhel A., Raindlova V., Havran L., Barek J., Hocek M., Fojta M.:
Voltammetric Study of dsDNA Modified by Multi-redox Label Based on N-methyl-4-hydrazino-7-nitrobenzofurazan.
Electrochimica Acta 129: 348-357, 2014.
 
162. Danhel A., Raindlova V., Havran L., Pivonkova H., Hocek M., Fojta M.:
Electrochemical behaviour of 2,4-dinitrophenylhydrazi(o)ne as multi-redox centre DNA label at mercury meniscus modified silversolid amalgam electrode.
Electrochimica Acta 126: 122-131, 2014.
 
161. Nauš P., Caletková O., Konečný P., Džubák P., Bogdanová K., Kolář M., Vrbková J., Slavětínská L., Tloušťová E., Perlíková P., Hajdúch M., Hocek M.:
Synthesis, Cytostatic, Antimicrobial, and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides.
Journal of Medicinal Chemistry 57: 1097-1110, 2014.

2013


160. Perlíková P., Konečný P., Nauš P., Snášel J., Votruba I., Džubák P., Pichová I., Hajdúch M., Hocek M.:
6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents.
MedChemComm 4: 1497-1500, 2013.
 
159. Daďová J., Vidláková P., Pohl R., Havran L., Fojta M., Hocek M.:
Aqueous Heck Cross-Coupling Preparation of Acrylate-Modified Nucleotides and Nucleoside Triphosphates for Polymerase Synthesis of Acrylate-Labeled DNA.
Journal of Organic Chemistry 78: 9627-9637, 2013.
 
158. Daďová J., Orság P., Pohl R., Brázdová M., Fojta M., Hocek M.:
Vinylsulfonamide and Acrylamide Modification of DNA for Crosslinking with Proteins.
Angewandte Chemie International Edition 52: 10515-10518, 2013.
 
157. Balintová J., Plucnara M., Vidláková P., Pohl R., Havran L., Fojta M., Hocek M.:
Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases.
Chemistry A European Journal 19: 12720-12731, 2013.
 
156. Tichý M., Pohl R., Tloušťová E., Weber J., Bahador G., Lee Y.-J., Hocek M.:
Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido [4,5-b]indole ribonucleosides.
Bioorganic & Medicinal Chemistry 21: 5362-5372, 2013.
 
155. Klečka M., Pohl R., Čejka J., Hocek M.:
Direct C–H sulfenylation of purines and deazapurines.
Organic & Biomolecular Chemistry 11: 5189-5193, 2013.
 
154. Kubelka T., Slavětínská L., Eigner V., Hocek M.:
Synthesis of 2,6-disubstituted pyridin-3-yl C-2'-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides.
Organic & Biomolecular Chemistry 11: 4702-4718, 2013.
 
153. Ménová P., Raindlová V., Hocek M.:
Scope and Limitations of the Nicking Enzyme Amplification Reaction for the Synthesis of Base-Modified Oligonucleotides and Primers for PCR.
Bioconjugate Chemistry 24: 1081-1093, 2013.
 
152. Kielkowski P., Brock N. L., Dickschat J. S., Hocek M.:
Nucleobase Protection Strategy for Gene Cloning and Expression.
ChemBioChem 14: 801-804, 2013.
 
151. Perlíková P., Eberlin L., Ménová P., Raindlová V., Slavětínská L., Tloušťová E., Bahador G., Lee Y.-J., Hocek M.:
Synthesis and Cytostatic and Antiviral Activities of 2'-Deoxy-2',2'-difluororibo- and 2'-Deoxy-2'-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines.
ChemMedChem 8: 832-846, 2013.
 
150. Ménová P., Cahová H., Plucnara M., Havran L., Fojta M., Hocek M.:
Polymerase synthesis of oligonucleotides containing a single chemically modified nucleobase for site-specific redox labelling.
Chemical Communications 49: 4652-4654, 2013.
 
149. Kalachová L., Pohl R., Bednárová L., Fanfrlík J., Hocek M.:
Synthesis of nucleosides and dNTPs bearing oligopyridine ligands linked through an octadiyne tether, their incorporation into DNA and complexation with transition metal cations.
Organic & Biomolecular Chemistry 11: 78-89, 2013.

2012


148. Riedl J., Ménová P., Pohl R., Orság P., Fojta M., Hocek M.:
GFP-like Fluorophores as DNA Labels for Studying DNA-Protein Interactions.
Journal of Organic Chemistry 77: 8287-8293, 2012.
 
147. Tichý M., Pohl R., Xu H. Y., Chen Y.-L., Yokokawa F., Shi P.-Y., Hocek M.:
Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides.
Bioorganic & Medicinal Chemistry 20: 6123-6133, 2012.
 
146. Kubelka T., Slavětínská L., Hocek M.:
Synthesis of Substituted Benzyl Homo-C-ribonucleosides and -nucleotides as Carba Analogues of Phosphoribosylanthranilate.
European Journal of Organic Chemistry: 4969-4981, 2012.
 
145. Riedl J., Pohl R., Ernsting N. P., Orság P., Fojta M., Hocek M.:
Labelling of nucleosides and oligonucleotides by solvatochromic 4-aminophthalimide fluorophore for studying DNA–protein interactions.
Chemical Science 3: 2797-2806, 2012.
 
144. Perlíková P., Jornet Martínez N., Slavětínská L., Hocek M.:
Synthesis of 2'-deoxy-2'-fluororibo- and 2'-deoxy-2',2'-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines.
Tetrahedron 68: 8300-8310, 2012.
 
143. Nauš P., Perlíková P., Bourderioux A., Pohl R., Slavětínská L., Votruba I., Bahador G., Birkuš G., Cihlář T., Hocek M.:
Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2'-C-methylribonucleosides, 2'-deoxy-2'-fluoroarabinonucleosides, arabinonucleosides and 2'-deoxyribonucleosides.
Bioorganic & Medicinal Chemistry 20: 5202-5214, 2012.
 
142. Raindlová V., Pohl R., Klepetářová B., Havran L., Šimková E., Horáková P., Pivoňková H., Fojta M., Hocek M.:
Synthesis of Hydrazone-Modified Nucleotides and Their Polymerase Incorporation onto DNA for Redox Labeling.
ChemPlusChem 77: 652-662, 2012.
 
141. Ménová P., Hocek M.:
Preparation of short cytosine-modified oligonucleotides by nicking enzyme amplification reaction.
Chemical Communications 48: 6921-6932, 2012.
 
140. Čerňová M., Pohl R., Klepetářová B., Hocek M.:
A General Regioselective Synthesis of 2,4-Diarylpyrimidines from 2-Thiouracil through Two Orthogonal Cross-Coupling Reactions.
Synlett 23: 1305-1308, 2012.
 
139. Raindlová V., Pohl R., Hocek M.:
Synthesis of Aldehyde-Linked Nucleotides and DNA and Their Bioconjugations with Lysine and Peptides through Reductive Amination.
Chemistry A European Journal 18: 4080-4087, 2012.
 
138. Chapuis H., Kubelka T., Joubert N., Pohl R., Hocek M.:
Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2'-Deoxyribonucleosides.
European Journal of Organic Chemistry: 1759-1767, 2012.
 
137. Kubelka T., Slavětínská L., Hocek M.:
A General Regioselective Approach to 2,4-Disubstituted Pyrimidin-5-yl C-2-Deoxyribonucleosides.
Synthesis 6: 953-965, 2012.
 
136. Riedl J., Pohl R., Rulíšek L., Hocek M.:
Synthesis and Photophysical Properties of Biaryl-Substituted Nucleos(t)ides. Polymerase Synthesis of DNA Probes Bearing Solvatochromic and pH-Sensitive Dual Fluorescent and 19F NMR Labels.
Journal of Organic Chemistry 77: 1026-1044, 2012.
 
135. Kalachová L., Pohl R., Hocek M.:
Synthesis of nucleoside mono- and triphosphates bearing oligopyridine ligands, their incorporation into DNA and complexation with transition metals.
Organic & Biomolecular Chemistry 10: 49-55, 2012.

2011


134. Balintová J., Pohl R., Horáková P., Vidláková P., Havran L., Fojta M., Hocek M.:
Anthraquinone as a Redox Label for DNA: Synthesis, Enzymatic Incorporation, and Electrochemistry of Anthraquinone-Modified Nucleosides, Nucleotides, and DNA.
Chemistry A European Journal 17: 14063-14073, 2011.
 
133. Hocek M., Fojta M.:
Nucleobase modification as redox DNA labelling for electrochemical detection.
Chemical Society Reviews 40: 5802-5814, 2011.
 
132. Kielkowski P., Macíčková-Cahová H., Pohl R., Hocek M.:
Transient and Switchable (Triethylsilyl)ethynyl Protection of DNA against Cleavage by Restriction Endonucleases.
Angewandte Chemie International Edition 50: 8727-8730, 2011.
 
131. Štambaský J., Kapras V., Štefko M., Kysilka O., Hocek M., Malkov A. V., Kočovský P.:
A Modular Approach to Aryl-C-ribonucleosides via the Allylic Substitution and Ring-Closing Metathesis Sequence. A Stereocontrolled Synthesis of All Four ?-/ß- and D-/L- C-Nucleoside Stereoisomers.
Journal of Organic Chemistry 76: 7781-7803, 2011.
 
130. Štefko M., Slavětínská L., Klepetářová B., Hocek M.:
General and Modular Synthesis of Isomeric 5-Substituted Pyridin-2-yl and 6-Substituted Pyridin-3-yl C-Ribonucleosides Bearing Diverse Alkyl, Aryl, Hetaryl, Amino, Carbamoyl, and Hydroxy Groups.
Journal of Organic Chemistry 76: 6619-6635, 2011.
 
129. Standara S., Bouzková K., Straka M., Zacharová Z., Hocek M., Marek J., Marek R.:
Interpretation of substituent effects on 13C and 15N NMR chemical shifts in 6-substituted purines.
Physical Chemistry Chemical Physics 13: 15854-15864, 2011.
 
128. Lund T. J., Cavanaugh N. A., Joubert N., Urban M., Patro J. N., Hocek M., Kuchta R. D.:
B Family DNA Polymerases Asymmetrically Recognize Pyrimidines and Purines.
Biochemistry 50: 7243-7250, 2011.
 
127. Nečas D., Hidasová D., Hocek M., Kotora M.:
Modular synthesis of 1-?- and 1-ß-(indol-2-yl)-2'-deoxyribose C-nucleosides.
Organic & Biomolecular Chemistry 9: 5934-5937, 2011.
 
126. Fojta M., Havran L., Pivoňková H., Horáková P., Hocek M.:
Redox Labels and Indicators Based on Transition Metals and Organic Electroactive Moieties for Electrochemical Nucleic Acids Sensing.
Current Organic Chemistry 15: 2936-2949, 2011.
 
125. Bourderioux A., Nauš P., Perlíková P., Pohl R., Pichová I., Votruba I., Džubák P., Konečný P., Hajdúch M., Stray K.M., Wang T., Ray A.S., Feng J.Y., Birkus G., Cihlar T., Hocek M.:
Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines.
Journal of Medicinal Chemistry 54: 5498-5507, 2011.
 
124. Čerňová M., Čerňa I., Pohl R., Hocek M.:
Regioselective Direct C-H Arylations of Protected Uracils. Synthesis of 5- and 6-Aryluracil Bases.
Journal of Organic Chemistry 76: 5309-5319, 2011.
 
123. Nauš P., Perlíková P., Pohl R., Hocek M.:
Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2'- C -methylribonucleosides, arabinonucleosides and 2'-deoxy-2'-fluoroarabinonucleosides.
Collection of Czechoslovak Chemical Communications 76: 957-988, 2011.
 
122. Stevens K., Claeys D.D., Catak S., Figaroli S., Hocek M., Tromp J.M., Schürch S., Speybroeck V., Madder A.:
Furan-Oxidation-Triggered Inducible DNA Cross-Linking: Acyclic Versus Cyclic Furan-Containing Building Blocks—On the Benefit of Restoring the Cyclic Sugar Backbone.
Chemistry A European Journal 17: 6940-6953, 2011.
 
121. Macíčková-Cahová H., Pohl R., Horáková P., Havran L., Špaček J., Fojta M., Hocek M.:
Alkylsulfanylphenyl Derivatives of Cytosine and 7-Deazaadenine Nucleosides, Nucleotides and Nucleoside Triphosphates: Synthesis, Polymerase Incorporation to DNA and Electrochemical Study.
Chemistry A European Journal 17: 5833-5841, 2011.
 
120. Kielkowski P., Pohl R., Hocek M.:
Synthesis of Acetylene Linked Double-Nucleobase Nucleos(t)ide Building Blocks and Polymerase Construction of DNA Containing Cytosines in the Major Groove.
Journal of Organic Chemistry 76: 3457-3462, 2011.
 
119. Horáková P., Macíčková-Cahová H., Pivoňková H., Špaček J., Havran L., Hocek M., Fojta M.:
Tail-labelling of DNA probes using modified deoxynucleotide triphosphates and terminal deoxynucleotidyl tranferase. Application in electrochemical DNA hybridization and protein-DNA binding assays.
Organic & Biomolecular Chemistry 9: 1366-1371, 2011.
 
118. Macíčková-Cahová H., Pohl R., Hocek M.:
Cleavage of Functionalized DNA Containing 5-Modified Pyrimidines by Type II Restriction Endonucleases.
ChemBioChem 12: 431-438, 2011.
 
117. Perlíková P., Pohl R., Votruba I., Shih R., Birkuš G., Cihlář T., Hocek M.:
Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides.
Bioorganic & Medicinal Chemistry 19: 229-242, 2011.

2010


116. Opekar S., Turek P., Pohl R., Klepetářová B., Votruba I., Hocek M., Kotora M.:
[2+2+2]-Cocyclotrimerization of 6-Alkynyl-7-benzylpurines with ?,?-Diynes.
Heterocycles 82: 895-907, 2010.
 
115. Štefko M., Hocek M.:
Synthesis of Phenol and Pyridone C-Ribo- and 2'-Deoxyribonucleosides by Palladium-Catalyzed Hydroxylations of Haloaryl C-Nucleosides.
Synthesis 24: 4199-4206, 2010.
 
114. Bárta J., Slavětínská L., Klepetářová B., Hocek M.:
Modular Synthesis of 5-Substituted Furan-2-yl C-2'-Deoxyribonucleosides and Biaryl Covalent Base-Pair Analogues.
European Journal of Organic Chemistry 2010: 5432-5443, 2010.
 
113. Spáčilová P., Nauš P., Pohl R., Votruba I., Snášel J., Zábranská H., Pichová I., Ameral R., Birkuš G., Cihlář T., Hocek M.:
CycloSal-phosphate Pronucleotides of Cytostatic 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Cytostatic Activity, and Inhibition of Adenosine Kinases.
ChemMedChem 5: 1386-1396, 2010.
 
112. Kubelka T., Slavětínská L., Klepetářová B., Hocek M.:
Synthesis of 2,4-Disubstituted Pyrimidin-5-yl C-2'-Deoxyribonucleosides by Sequential Regioselective Reactions of 2,4-Dichloropyrimidine Nucleosides.
European Journal of Organic Chemistry 2010: 2666-2669, 2010.
 
111. Marek R., Křístková A., Maliňáková K., Toušek J., Marek J., Hocek M., Malkina O.L., Malkin V.G.:
Interpretation of Indirect Nuclear Spin-Spin Couplings in Isomers of Adenine: Novel Approach to Analyze Coupling Electron Deformation Density Using Localized Molecular Orbitals.
The Journal of Physical Chemistry A 114: 6689-6700, 2010.
 
110. Standara S., Maliňáková K., Marek R., Marek J., Hocek M., Vaara J., Straka M.:
Understanding the NMR chemical shifts for 6-halopurines: role of structure, solvent and relativistic effects.
Physical Chemistry Chemical Physics 12: 5126-5139, 2010.
 
109. Čerňa I., Pohl R., Klepetářová B., Hocek M.:
Intramolecular Direct C-H Arylation Approach to Fused Purines. Synthesis of Purino[8,9-f]phenanthridines and 5,6-Dihydropurino[8,9-a]isoquinolines.
Journal of Organic Chemistry 75: 2302-2308, 2010.
 
108. Hasník Z., Pohl R., Hocek M.:
Synthesis of (purin-6-yl)methylphosphonate bases and nucleosides.
Tetrahedron 51: 2464-2466, 2010.
 
107. Raindlová V., Pohl R., Šanda M., Hocek M.:
Direct Polymerase Synthesis of Reactive Aldehyde-Functionalized DNA and Its Conjugation and Staining with Hydrazines.
Angewandte Chemie International Edition 49: 1064-1066, 2010.
 
106. Macíčková-Cahová H., Vrábel M., Hocek M.:
Cross-Coupling Modification of Nucleoside Triphosphates, PEX, and PCR Construction of Base-Modified DNA.
Current Protocols in Chemical Biology 2: 1-14, 2010.
 
105. Ikonen S., Macíčková-Cahová H., Pohl R., Šanda M., Hocek M.:
Synthesis of nucleoside and nucleotide conjugates of bile acids, and polymerase construction of bile acid-functionalized DNA.
Organic & Biomolecular Chemistry 8: 1194-1201, 2010.
 
104. Urban M., Joubert N., Purse B.W., Hocek M., Kuchta R. D.:
Mechanisms by Which Human DNA Primase Chooses To Polymerize a Nucleoside Triphosphate.
Biochemistry 49: 727-735, 2010.
 
103. Štefko M., Slavětínská L., Klepetářová B., Hocek M.:
A General and Efficient Synthesis of Pyridin-2-yl C-Ribonucleosides Bearing Diverse Alkyl, Aryl, Amino, and Carbamoyl Groups in Position 6.
Journal of Organic Chemistry 75: 442-449, 2010.
 
102. Nauš P., Pohl R., Votruba I., Džubák P., Hajdúch M., Ameral R., Birkus G., Wang T., Ray A.S., Mackman R., Cihlar T., Hocek M.:
6-(Het)aryl-7-Deazapurine Ribonucleosides as Novel Potent Cytostatic Agents.
Journal of Medicinal Chemistry 53: 460-470, 2010.
 
101. Bobula T., Hocek M., Kotora M.:
Sonogashira reactions of ?- and ß-1-ethynyl-2-deoxyribosides: synthesis of acetylene-extended C-nucleosides.
Tetrahedron 66: 530-536, 2010.

2009


100. Macíčková-Cahová H., Hocek M.:
Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases.
Nucleic Acids Research 37: 7612-7622, 2009.
 
99. Štambaský J., Hocek M., Kočovský P.:
C-Nucleosides: Synthetic Strategies and Biological Applications.
Chemical Reviews 109: 6729-6764, 2009.
 
98. Urban M., Joubert N., Hocek M., Alexander R. E., Kuchta R. D.:
Herpes Simplex Virus-1 DNA Primase: A Remarkably Inaccurate yet Selective Polymerase.
Biochemistry 48: 10866-10881, 2009.
 
97. Zendlová L., Řeha D., Hocek M., Hobza P.:
Theoretical Study of the Stability of the DNA Duplexes Modified by a Series of Hydrophobic Base Analogues.
Chemistry A European Journal 15: 7601-7610, 2009.
 
96. Čerňová M., Pohl R., Hocek M.:
Switching the Regioselectivity of Direct C–H Arylation of 1,3-Dimethyluracil.
European Journal of Organic Chemistry 2009: 3698-3701, 2009.
 
95. Hasník Z., Pohl R., Klepetářová B., Hocek M.:
Synthesis of (Purin-6-yl)acetates and Their Transformations to 6-(2-Hydroxyethyl)- and 6-(Carbamoylmethyl)purines.
Collection of Czechoslovak Chemical Communications 74: 1035-1059, 2009.
 
94. Riedl J., Horáková P., Šebest P., Pohl R., Havran L., Fojta M., Hocek M.:
Tetrathiafulvalene-Labelled Nucleosides and Nucleoside Triphosphates: Synthesis, Electrochemistry and the Scope of Their Polymerase Incorporation into DNA.
European Journal of Organic Chemistry 2009: 3519-3525, 2009.
 
93. Štefko M., Pohl R., Hocek M.:
Synthesis of benzamide- C -ribonucleosides by Pd-catalyzed aminocarbonylations.
Tetrahedron 65: 4471-4483, 2009.
 
92. Hasník Z., Pohl R., Klepetářová B., Hocek M.:
Cross-Coupling Reactions of Halopurines with Aryl- and Alkyltrifluoro­borates; The Scope and Limitations in the Synthesis of Modified Purines.
Synthesis 8: 1309-1317, 2009.
 
91. Klečka M., Pohl R., Klepetářová B., Hocek M.:
Direct C–H borylation and C–H arylation of pyrrolo[2,3- d ]pyrimidines: synthesis of 6,8-disubstituted 7-deazapurines.
Organic & Biomolecular Chemistry 7: 866-868, 2009.
 
90. Vrábel M., Horáková P., Pivoňková H., Kalachova L., Černocká H., Cahová H., Pohl R., Šebest P., Havran L., Hocek M., Fojta M. :
Base-Modified DNA Labeled by [Ru(bpy) 3 ] 2+ and [Os(bpy) 3 ] 2+ Complexes: Construction by Polymerase Incorporation of Modified Nucleoside Triphosphates, Electrochemical and Luminescent Properties, and Applications.
Chemistry A European Journal 15: 1144-1154, 2009.
 
89. Kalachová L., Pohl R., Hocek M.:
Synthesis of 2'-Deoxyuridine and 2'-Deoxycytidine Nucleosides Bearing Bipyridine and Terpyridine Ligands at Position 5.
Synthesis 1: 105-112, 2009.

2008


88. Hari Y., Hwang G. T., Leconte A. M., Joubert N., Hocek M., Romesberg F. E.:
Optimization of the Pyridyl Nucleobase Scaffold for Polymerase Recognition and Unnatural Base Pair Replication.
ChemBioChem 9: 2796-2799, 2008.
 
87. Čerňa I., Pohl R., Klepetářová B., Hocek M.:
Synthesis of 6,8,9-Tri- and 2,6,8,9-Tetrasubstituted Purines by a Combination of the Suzuki Cross-coupling, N-Arylation, and Direct C-H Arylation Reactions.
Journal of Organic Chemistry 73: 9048-9054, 2008.
 
86. Cahová H., Pohl R., Bednárová L., Nováková K., Cvačka J., Hocek M.:
Synthesis of 8-bromo-, 8-methyl- and 8-phenyl-dATP and their polymerase incorporation into DNA.
Organic & Biomolecular Chemistry 6: 3657-3660, 2008.
 
85. Kuchař M., Pohl R., Klepetářová B., Hocek M.:
Synthesis of diverse 6-(1,2-disubstituted ethyl)purine bases and nucleosides via 6-(oxiran-2-yl)purines.
Tetrahedron 64: 10355-10364, 2008.
 
84. Srnec M., Chalupský J., Fojta M., Zendlová L., Havran L., Hocek M., Kývala M., Rulíšek M.:
Effect of Spin-Orbit Coupling on Reduction Potentials of Octahedral Ruthenium(II/III) and Osmium(II/III) Complexes.
Journal of American Chemical Society 130: 10947-10954, 2008.
 
83. Vrábel M., Pohl R., Votruba I., Sajadi M., Kovalenko S. A., Ernsting N. P., Hocek M.:
Synthesis and photophysical properties of 7-deaza-2'-deoxyadenosines bearing bipyridine ligands and their Ru(II)-complexes in position 7.
Organic & Biomolecular Chemistry 6: 2852-2860, 2008.
 
82. Nauš P., Kuchař M., Hocek M.:
Cytostatic and activiral 6-arylpurine ribonucleosides IX. Synthesis and evaluation of 6-substituted 3-deazapurine ribonuclesides.
Collection of Czechoslovak Chemical Communications 73: 665-678, 2008.
 
81. Hocek M., Fojta M.:
Cross-coupling reactions of nucleoside triphosphates followed by polymerase incorporation. Construction and applications of base-functionalized nucleic acids.
Organic & Biomolecular Chemistry 6: 2233-2241, 2008.
 
80. Kuchař M., Pohl R., Klepetářová B., Votruba I., Hocek M.:
Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations.
Organic & Biomolecular Chemistry 6: 2377-2387, 2008.
 
79. Turek P., Hocek M., Pohl R., Klepetářová B., Kotora M.:
Cobalt-Induced Synthesis of 6-(Pyridin-2-yl)purines by Microwave-Enhanced [2+2+2] Cyclotrimerization.
European Journal of Organic Chemistry 2008: 3335-3343, 2008.
 
78. Joubert N., Bambuch V., Pohl R., Hocek M.:
Modular Synthesis of 4-Aryl- and 4-Amino-Substituted Benzene C -2'-Deoxyribonucleosides.
Synthesis 12: 1918-1932, 2008.
 
77. Bambuch V., Pohl R., Hocek M.:
Synthesis of 6-(4,5-Dihydrofuran-2-yl)- and 6-(Tetrahydrofuran-2-yl)purine Bases and Nucleosides.
European Journal of Organic Chemistry 2008: 2783-2788, 2008.
 
76. Bárta J., Pohl R., Klepetářová B., Ernsting N. P., Hocek M.:
Modular Synthesis of 5-Substituted Thiophen-2-yl C -2'-Deoxyribonucleosides.
Journal of Organic Chemistry 73: 3798-3806, 2008.
 
75. Novák P., Číhalová S., Otmar M., Hocek M., Kotora M.:
Co- and homocyclotrimerization reactions of protected 1-alkynyl-2-deoxyribofuranose. Synthesis of C -nucleosides, C -di- and C -trisaccharide analogues.
Tetrahedron 64: 5200-5207, 2008.
 
74. Šilhár P., Hocek M., Pohl R., Votruba I., Shih I., Mabery E., Mackman R.:
Synthesis, cytostatic and anti-HCV activity of 6-( N -substituted aminomethyl)-, 6-( O -substituted hydroxymethyl)- and 6-( S -substituted sulfanylmethyl)purine nucleosides.
Bioorganic & Medicinal Chemistry 16: 2329-2366, 2008.
 
73. Štefko M., Pohl R., Klepetářová B., Hocek M.:
A Modular Methodology for the Synthesis of 4- and 3-Substituted Benzene and Aniline C-Ribonucleosides.
European Journal of Organic Chemistry 2008: 1689-1704, 2008.
 
72. Cahová H., Havran L., Brázdilová P., Pivoňková H., Pohl R., Fojta M., Hocek M.:
Aminophenyl- and Nitrophenyl-Labeled Nucleoside Triphosphates: Synthesis, Enzymatic Incorporation, and Electrochemical Detection.
Angewandte Chemie International Edition 47: 2059-2062, 2008.
 
71. Hasník Z., Šilhár P., Hocek M.:
Hydroxymethylations of Aryl Halides by Pd-Catalyzed Cross-Couplings with (Benzoyloxy)methylzinc Iodide – Scope and Limitations of the Reaction.
Synlett 4: 543-546, 2008.
 
70. Kuchař M., Hocek M., Pohl R., Votruba I., Shih I., Mabery E., Mackman R.:
Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides.
Bioorganic & Medicinal Chemistry 16: 1400-1424, 2008.

2007


69. Brázdilová P., Vrábel M., Pohl R., Pivoňková H., Havran L., Hocek M., Fojta M.:
Ferrocenylethynyl Derivatives of Nucleoside Triphosphates: Synthesis, Incorporation, Electrochemistry, and Bioanalytical Applications.
Chemistry A European Journal 13: 9527-9533, 2007.
 
68. Čerňa I., Pohl R., Hocek M.:
The first direct C–H arylation of purine nucleosides.
Chemical Communications: 4729-4730, 2007.
 
67. Joubert N., Pohl R., Klepetářová B., Hocek M.:
Modular and Practical Synthesis of 6-Substituted Pyridin-3-yl C-Nucleosides.
Journal of Organic Chemistry 72: 6797-6805, 2007.
 
66. Vrábel M., Pohl R., Klepetářová B., Votruba I., Hocek M.:
Synthesis of 2'-deoxyadenosine nucleosides bearing bipyridine-type ligands and their Ru-complexes in position 8 through cross-coupling reactions.
Organic & Biomolecular Chemistry 5: 2849-2857, 2007.
 
65. Hasník Z., Šilhár P., Hocek M. :
Synthesis of (purin-6-yl)acetates and 6-(2-hydroxyethyl)purines via cross-couplings of 6-chloropurines with the Reformatsky reagent.
Tetrahedron Letters 48: 5589-5592, 2007.
 
64. Čapek P., Cahová H., Pohl R., Hocek M., Gloeckner C., Marx A.:
An Efficient Method for the Construction of Functionalized DNA Bearing Amino Acid Groups through Cross-Coupling Reactions of Nucleoside Triphosphates Followed by Primer Extension or PCR.
Chemistry A European Journal 13: 6196-6203, 2007.
 
63. Hocek M., Šilhár P.:
Palladium-Catalyzed Cross-Coupling Reactions in C6 Modifications of Purine Nucleosides.
Current Protocols in Nucleic Acid Chemistry: 1.16, 2007.
 
62. Vrábel M., Hocek M., Havran L., Fojta M., Votruba I., Klepetářová B., Pohl R., Rulíšek L., Zendlová L., Hobza P., Shih I., Mabery E., Mackman R.:
Purines Bearing Phenanthroline or Bipyridine Ligands and Their Ru II Complexes in Position 8 as Model Compounds for Electrochemical DNA Labeling – Synthesis, Crystal Structure, Electrochemistry, Quantum Chemical Calculations, Cytostatic and Antiviral Activity.
European Journal of Inorganic Chemistry 2007: 1752-1769, 2007.
 
61. Beckman J., Kincaid K., Hocek M., Spratt T., Engels J., Cosstick R., Kuchta R. D.:
Human DNA Polymerase ? Uses a Combination of Positive and Negative Selectivity To Polymerize Purine dNTPs with High Fidelity.
Biochemistry 46: 448-460, 2007.

2006


60. Čerňa I., Pohl R., Klepetářová B., Hocek M.:
Direct C-H Arylation of Purines: Development of Methodology and Its Use in Regioselective Synthesis of 2,6,8-Trisubstituted Purines.
Organic Letters 8: 5389-5392, 2006.
 
59. Hocek M., Šilhár P., Pohl R.:
Cytostatic and activiral 6-arylpurine ribonucleosides VIII. Synthesis and evaluation of 6-substituted purine 3'-deoxyribonucletides.
Collection of Czechoslovak Chemical Communications 71: 1484-1496, 2006.
 
58. Turek P., Novák P., Pohl R., Hocek M., Kotora M.:
Preparation of Highly Substituted 6-Arylpurine Ribonucleosides by Ni-Catalyzed Cyclotrimerization. Scope of the Reaction.
Journal of Organic Chemistry 71: 8978-8981, 2006.
 
57. Kuchař M., Pohl R., Votruba I., Hocek M.:
Synthesis of Purines Bearing Functionalized C-Substituents by the Conjugate Addition of Nucleophiles to 6-Vinylpurines and 6-Ethynylpurines.
European Journal of Organic Chemistry 2006: 5083-5098, 2006.
 
56. Čapek P., Vrábel M., Hasník Z., Pohl R., Hocek M.:
Aqueous-Phase Suzuki-Miyaura Cross-Coupling Reactions of Free Halopurine Bases.
Synthesis 20: 3515-3526, 2006.
 
55. Hocek M., Šilhár P., Shih I., Mabery E., Mackman R.:
Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: Synthesis and evaluation of 6-substituted purine L-ribonucleosides.
Bioorganic & Medicinal Chemistry Letters 16: 5290-5293, 2006.
 
54. Urban M., Pohl R., Klepetářová B., Hocek M.:
New Modular and Efficient Approach to 6-Substituted Pyridin-2-yl C-Nucleosides.
Journal of Organic Chemistry 71: 7322-7328, 2006.
 
53. Čapek P., Pohl R., Hocek M.:
Cross-coupling reactions of unprotected halopurine bases, nucleosides, nucleotides and nucleoside triphosphates with 4-boronophenylalanine in water. Synthesis of (purin-8-yl)- and (purin-6-yl)phenylalanines.
Organic & Biomolecular Chemistry 4: 2278-2284, 2006.
 
52. Šilhár, P., Pohl R., Votruba I., Klepetářová B., Hocek M.:
Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl- 2-(Hydroxymethyl)purine Bases and Nucleosides.
Collection of Czechoslovak Chemical Communications 71: 788-803, 2006.
 
51. Šilhár, P., Pohl R., Votruba I., Hocek M.:
Synthesis and Cytostatic Activity of Novel 6-(Difluoromethyl)purine Bases and Nucleosides.
Synthesis 11: 1848-1852, 2006.
 
50. Novák P., Pohl R., Kotora M., Hocek M.:
Synthesis of C-Aryldeoxyribosides by [2 + 2 + 2]-Cyclotrimerization Catalyzed by Rh, Ni, Co, and Ru Complexes.
Organic Letters 8: 2051-2054, 2006.
 
49. Řeha D., Hocek M., Hobza P.:
Exceptional Thermodynamic Stability of DNA Duplexes Modified by Nonpolar Base Analogues Is due to Increased Stacking Interactions and Favorable Solvation: Correlated Ab Initio Calculations and Molecular Dynamics Simulations.
Chemistry A European Journal 12: 3587-3595, 2006.

2005


48. Šilhár P., Pohl R., Votruba I., Hocek M.:
Synthesis of 2-Substituted 6-(Hydroxymethyl)Purine Bases and Nucleosides.
Collection of Czechoslovak Chemical Communications 70: 1669-1695, 2005.
 
47. Čapek P., Hocek M.:
Efficient One-Step Synthesis of Optically Pure (Adenin-8-yl)phenylalanine Nucleosides.
Synlett 19: 3005-3007, 2005.
 
46. Hocek M., Pohl R., Klepetářová B.:
A New Modular and Practical Methodology for the Synthesis of 4- or 3-Substituted Phenyl C-Nucleosides.
European Journal of Organic Chemistry 2005: 4525-4528, 2005.
 
45. Čapek P., Pohl R., Hocek M.:
Synthesis of Enantiomerically Pure (Purin-6-yl)phenylalanines and Their Nucleosides, a Novel Type of Purine-Amino Acid Conjugates.
Journal of Organic Chemistry 70: 8001-8008, 2005.
 
44. Hocek M., Nauš P., Pohl R., Votruba I., Furman P. A., Tharnish P. M., Otto M. J.:
Cytostatic 6-Arylpurine Nucleosides. 6. SAR in Anti-HCV and Cytostatic Activity of Extended Series of 6-Hetarylpurine Ribonucleosides.
Journal of Medicinal Chemistry 48: 5869-5873, 2005.
 
43. Šilhár P., Pohl R., Votruba I., Hocek M.,:
The First Synthesis and Cytostatic Activity of Novel 6-(Fluoromethyl)purine Bases and Nucleosides.
Organic & Biomolecular Chemistry 3: 3001-3007, 2005.
 
42. Hocek M., Pohl R., Císařová I.:
Highly Methylated Purines and Purinium Salts as Analogues of Heteromines.
European Journal of Organic Chemistry 2005: 3026-3030, 2005.
 
41. Turek P., Kotora M., Hocek M., Votruba I.:
Novel Method for Preparation of Highly Substituted 6-Arylpurines by Reactions of 6-Alkynylpurines with Zirconacyclopentadienes.
Collection of Czechoslovak Chemical Communications 70: 339-349, 2005.

2004


40. Turek P., Kotora M., Tišlerová I., Hocek M., Votruba I., Císařová I.:
Cocyclotrimerization of 6-Alkynylpurines with ?,?-Diynes as a Novel Approach to Biologically Active 6-Arylpurines.
Journal of Organic Chemistry 69: 9224-9233, 2004.
 
39. Hocek M., Pohl R.:
Regioselectivity in Cross-Coupling Reactions of 2,6,8-Trichloro-9-(tetrahydropyran-2-yl)purine: Synthesis of 2,6,8-Trisubstituted Purine Bases.
Synthesis 17: 2869-2876, 2004.
 
38. Čapek P., Pohl R., Hocek M.:
A Facile and Efficient Synthesis of (Purin-6-yl)alanines.
Journal of Organic Chemistry 69: 7985-7988, 2004.
 
37. Nauš P., Votruba I., Hocek M.:
Covalent Analogues of DNA Base-Pairs and Triplets VII. Synthesis and Cytostatic Activity of Bis(purin-6-yl)acetylene and -diacetylene Nucleosides.
Collection of Czechoslovak Chemical Communications 69: 1955-1970, 2004.
 
36. Šilhár P., Pohl R., Votruba I., Hocek M.:
Facile and Efficient Synthesis of 6-(Hydroxymethyl)purines.
Organic Letters 6: 3225-3228, 2004.
 
35. Sečkářová P., Marek R., Maliňáková K., Kolehmainen E., Hocková D., Hocek M., Sklenář V.:
Direct Determination of Tautomerism in Purine Derivatives by Low-Temperature NMR Spectroscopy.
Tetrahedron Letters 45: 6259-6263, 2004.
 
34. Hocek M.:
Synthesis of Protected (Purin-6-yl)glycines via Pd-Catalyzed ?-Arylation of Ethyl N-(Diphenylmethylidene)glycinate with 6-Iodopurines.
Heterocycles 63: 1673-1677, 2004.
 
33. Hocek M., Hocková D., Dvořáková D.:
Dichotomy in Regioselective Cross-Coupling Reactions of 6,8-Dichloropurines with Phenylboronic Acid and Methylmagnesium Chloride: Synthesis of 6,8-Disubstituted Purines.
Synthesis 6: 889-894, 2004.
 
32. Hocek M., Štěpnička P., Ludvík J., Císařová I., Votruba I., Řeha D., Hobza P.:
Ferrocene-Modified Purines as Potential Electrochemical Markers: Synthesis, Crystal Structures, Electrochemistry and Cytostatic Activity of (Ferrocenylethynyl)- and (Ferrocenylethyl)purines.
Chemistry A European Journal 10: 2058-2066, 2004.

2003


31. Hocek M.:
C-C and C-X Bond Formation by Cross-coupling Reactions Catalyzed by Transition Metal Complexes (in Czech).
Chemické Listy 97: 1145-1150, 2003.
 
30. Hocek M., Dvořák D., Havelková M.:
Covalent Analogues of Nucleobase-Pairs.
Nucleosides, Nucleotides and Nucleic Acids 22: 775-777, 2003.
 
29. Hocek M., Dvořáková H.:
An Efficient Synthesis of 2-Substituted 6-Methylpurine Bases and Nucleosides by Fe- or Pd-Catalyzed Cross-Coupling Reactions of 2,6-Dichloropurines.
Journal of Organic Chemistry 68: 5773-5776, 2003.
 
28. Hocek M., Hocková D., Štambaský J.:
Cytostatic 6-Arylpurine Nucleosides V. Synthesis of 8-Substituted 6-Phenylpurine Ribonucleosides.
Collection of Czechoslovak Chemical Communications 68: 837-848, 2003.
 
27. Turek P., Kotora M., Hocek M., Císařová, I.:
[2+2+2]-Co-cyclotrimerization of 6-Alkynylpurines with Diynes: a Method for Preparation 6-Arylpurines.
Tetrahedron Letters 44: 785-788, 2003.
 
26. Hocek M., Votruba I., Dvořáková H.:
Synthesis of Carba-Analogues of Myoseverine by Regioselective Cross-coupling Reactions of 2,6-Dichloro-9-isopropylpurine.
Tetrahedron 59: 607-611, 2003.
 
25. Hocek M.:
Syntheses of Purines Bearing Carbon Substituents in Positions 2, 6 or 8 by Metal- or Organometallics-Mediated C-C Bond Forming Reactions.
European Journal of Organic Chemistry 2003: 245-254, 2003.

2002


24. Hocek M., Dvořáková H., Císařová I.:
Covalent Analogues of DNA Base-Pairs and Triplets V. Synthesis of Purine-Purine and Purine-Pyrimidine Conjugates Connected By Diverse Types of Acyclic Carbon Linkages.
Collection of Czechoslovak Chemical Communications 67: 1560-1578, 2002.
 
23. Hocek M., Starý I., Stará I. G., Dvořáková H.:
Covalent Analogues of DNA Base-Pairs and Triplets IV. Synthesis of trisubstituted benzenes bearing purine and/or pyrimidine rings by cyclotrimerization of 6-ethynylpurines and/or 5-ethynyl-1,3-dimethyluracil.
Collection of Czechoslovak Chemical Communications 67: 1223-1235, 2002.
 
22. Havelková M., Dvořák D., Hocek M.:
Covalent Analogues of DNA Base-Pairs and Triplets III. Synthesis of 1,4- and 1,3-bis(purin-6-yl)benzenes and 1-(1,3-dimethyluracil-5-yl)-3 or 4-(purin-9-yl)benzenes.
Tetrahedron 58: 7431-7435, 2002.
 
21. Hocek M., Holý A., Dvořáková H.:
Cytostatic 6-Arylpurine Nucleosides IV. Synthesis of 2-Substituted 6-Phenylpurine Ribonucleosides.
Collection of Czechoslovak Chemical Communications 67: 325-335, 2002.
 
20. Hocek M., Votruba I.:
Covalent Analogues of DNA Base-Pairs and Triplets II. Synthesis and Cytostatic Activity of is(purin-6-yl)acetylenes, -diacetylenes and Related Compounds.
Bioorganic & Medicinal Chemistry Letters 12: 1055-1057, 2002.

2001


19. Havelková M., Dvořák D., Hocek M.:
The Suzuki-Miyaura Cross-Coupling Reactions of 2-, 6- or 8-Halopurines with Boronic Acids Leading to 2-, 6- or 8-Aryl- or -Alkenylpurine Derivatives.
Synthesis 11: 1704-1710, 2001.
 
18. Hocek M., Holý A., Votruba I., Dvořáková H.:
Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides.
Collection of Czechoslovak Chemical Communications 66: 483-499, 2001.
 
17. Hocek M., Starý I., Stará I. G., Dvořáková H.:
Cyclotrimerization of 6-ethynylpurines. Synthesis of 1,2,4- and 1,3,5-tris(purin-6-yl)benzenes as novel Hoogsteen-triplet analogues.
Tetrahedron Letters 42: 519-521, 2001.

2000


16. Hocek M., Holý A., Votruba I., Dvořáková H.:
Cytostatic 6-Arylpurine Nucleosides II. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-ß-D- erythro- pentofuranosyl)-, 9-(5-Deoxy-ß-D-ribofuranosyl)- and 9-(2,3-dihydroxypropyl)-6-phenylpurines.
Collection of Czechoslovak Chemical Communications 65: 1683-1697, 2000.
 
15. Hocek M.: Synthesis and Biological Activity of 2- and 6- C -Substituted Purine Bases, Nuceosides and Acyclic Nucleotide Analogues - Alfred Bader Award Lecture (in Czech).
Chemické Listy 94: 978-982, 2000.
 
14. Česnek M, Hocek M., Holý A.:
Synthesis of Acyclic Nucleotide Analogues Derived from 2-Amino-6-C-substituted Purines via Cross-Coupling Reactions of 2-Amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with Diverse Organometallic Reagents.
Collection of Czechoslovak Chemical Communications 65: 1357-1373, 2000.
 
13. Hocek M., Holý A., Votruba I., Dvořáková H.:
Synthesis and Cytostatic Activity of Substituted 6-Phenylpurine Bases and Nucleosides:?Application of the Suzuki-Miyaura Cross-Coupling Reactions of 6-Chloropurine Derivatives with Phenylboronic Acids.
Journal of Medicinal Chemistry 43: 1817-1825, 2000.

1999


12. Hocková D., Hocek M., Dvořáková H., Votruba I.:
Synthesis and Cytostatic Activity of Nucleosides and Acyclic Nucleoside Analogues Derived from 6-(Trifluoromethyl)purines.
Tetrahedron 55: 11109-11118, 1919.
 
11. Havelková M., Hocek M., Česnek M., Dvořák D.:
The Suzuki-Miyaura Cross-Coupling Reactions of 6-Halopurines with Boronic Acids Leading to 6-Aryl and 6-Alkenylpurines.
Synlett 7: 1145-1147, 1919.
 
10. Hocek M., Holý A.:
Perfluoroalkylation of 6-Iodopurines by Trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(Perfluoroalkyl)purine Bases, Nucleosides and Acyclic Nucleotide Analogues.
Collection of Czechoslovak Chemical Communications 64: 229-241, 1919.

1997


9. Hocek M., Masojídková M., Holý A.:
Synthesis of Acyclic Nucleotide Analogues Derived from 6-Hetarylpurines via Cross-Coupling Reactions of 9-[2-(Diethoxyphosphonylmethoxy)ethyl]-6-iodopurine with Hetaryl Organometallic Reagents.
Collection of Czechoslovak Chemical Communications 62: 136-146, 1997.
 
8. Hocek M., Masojídková M., Holý A.:
Synthesis of Acyclic Nucleotide Analogues Derived from N -Substituted 6-(1-Aminoethyl)purines via 6-Acetylpurine Derivatives.
Tetrahedron 53: 2291-2302, 1997.

1996


7. Hocek M., Masojídková M., Holý A., Andrei G., Snoeck R., Balzarini J., De Clercq E.:
Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines.
Collection of Czechoslovak Chemical Communications 61: 1525-1537, 1996.
 
6. Hocek M., Holý A.: Acyclic Nucleotide Analogues Derived from 6-(1-Aminoalkyl)purines.
Collection of Czechoslovak Chemical Communications 61 (Special issue): S55-S58, 1996.

1995


5. Hocek M., Holý A.:
A Facile Synthesis of 6-Cyanopurines.
Collection of Czechoslovak Chemical Communications 60: 1386-1389, 1995.
 
4. Hocek M., Masojídková M., Holý A.:
Synthesis of Acyclic Nucleotide Analogues Derived from 2-(Aminomethyl)adenine and 2-(Aminomethyl)hypoxanthine.
Collection of Czechoslovak Chemical Communications 60: 875-882, 1995.

1994


3. Hocek M., Masojídková M., Holý A.:
A Facile Synthesis of 2-(Aminomethyl)Purines.
Synthesis 12: 1401-1402, 1994.
 
2. Böhm S., Hocek M., Němeček J., Havlíček V., Kuthan J.:
Preparation and Spectroscopic Properties of Spirocyclic 1-Methyl-2,4,4,6-tetraaryl-1,4-dihydropyridines.
Collection of Czechoslovak Chemical Communications 59: 1105-1114, 1994.
 
1. Böhm S., Hocek M., Nešpůrek S., Kuthan J.:
Photocolouration of 2,4,4,6-Tetraaryl-1,4-dihydropyridines: A Semiempirical Quantum Chemical Study.
Collection of Czechoslovak Chemical Communications 59: 262-272, 1994.