Laboratory of Growth Substances
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and Institute of Experimental Botany, Academy of Sciences of the Czech Republic (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Workers
head of the laboratorysenior scientist
- Prof. ing. Miroslav Strnad CSc.
scientist
- Jiří Grúz
- Mgr. Ondřej Novák Ph.D.
- Mgr. Lucie Plíhalová Ph.D.
- Mgr. Danuše Tarkowská Ph.D.
- PharmDr. Lubor Urbánek Ph.D.
graduated technical assistant
- Mgr. Ota Blahoušek
- Ivan Petřík
assistant
- Jitka Hansgutová DiS.
technician
- Mgr. Marie Karlická
Research projects
Publications
2011
- BIOINFORMATICS 27 (10) 1404-1412 2011 (External fulltext)
- COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS 76 1669–1686 2011 (External fulltext)
2010
- NEW PHYTOLOGIST in press: DOI: 10.1111/j.1469-8137.2010.03387.x 2010 Fulltext: public PDF link
2009
- JOURNAL OF CHROMATOGRAPHY 1100 [1] 116-125 2009
- PHYSIOLOGIA PLANTARUM 118 [1] 127-137 2009
2008
- JOURNAL OF PLANT GROWTH REGULATION 27 271-281 2008 Fulltext: PDF link on intranet only
2007
- BIOORGANIC AND MEDICAL CHEMISTRY 15 [11] 3737-3747 2007 Fulltext: public PDF link
- JOURNAL OF BIOLOGICAL CHEMISTRY 282 [19] 14356-14363 2007 Fulltext: public PDF link
- JOURNAL OF CHROMATOGRAPHY Analytical Technologies in the Biomedical and Life Sciences 847 [2] 162-173 2007 Fulltext: public PDF link
- JOURNAL OF FOOD QUALITY 30 [6] 1040-1055 2007 Fulltext: public PDF link