Dr. Hubert Chapuis

e-mail: chapuis@uochb.cas.cz
phone: +420 220183108


Born 17. 10. 1978 in Saint-Etienne (France).

Scientific CV:
2001-2002 Undergraduate study at the Laboratoire de Chimie Organique - Photochimie et Synthese (supervisor Professor Olivier Piva and Doctor Fabienne Fache)
2002-2006 Ph.D. study at Université Claude Bernard Lyon 1, Lyon, France (supervisor Professor Peter Strazewski)
2006-2008 Postdoctoral position at the Université Victor Segalen Bordeaux 2, Bordeaux, France (supervisor Professor Philippe Barthélémy)
since 2008 Postdoctoral position at the Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic

List of publications:

6.	Chapuis, H.; Kubelka, T.; Joubert, N.; Pohl, R.; Hocek, M.: "Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2'-Deoxyribonucleosides" Eur. J. Org. Chem. 2012, 1759-1767.
5.	Gissot, A.; Di Primo, C. ; Bestel, I. ; Giannone, G. ; Chapuis, H.; Barthélémy, P.: "Sensitive liposomes encoded with oligonucleotide amphiphiles: a biocompatible switch" Chem. Commun. 2008, in press.
4.	Chapuis, H.; Bui, L.; Bestel, I.; Barthélémy, P.: "2'-Lipid-modified oligonucleotides via a 'Staudinger-Vilarrasa' reaction" Tetrahedron Lett. 2008, 49, 6838-6840.
3.	Charafeddine, A. ; Chapuis, H. ; Strazewski, P.: "Facile and Rapid Access to Inosine Puromycin Analogues through the Use of Adenylate Deaminase" Org. Lett. 2007, 9, 2787-2790.
2.	Charafeddine, A.; Dayoub, W.; Chapuis, H.; Strazewski, P.: "First synthesis of 2'-deoxyfluoropuromycin analogues: Experimental insight into the mechanism of the Staudinger reaction" Chemistry-A European Journal 2007, 13, 5566-5584.
1.	Chapuis, H.; Strazewski, P.: "Shorter puromycin analog synthesis by means of an efficient Staudinger-Vilarrasa coupling" Tetrahedron 2006, 62, 12108-12115.