| |
| Education |
| 1990-1995 |
Ph.D. in Biochemistry, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague. |
| 1981-1986 |
M.Sc. (Mgr.) in Inorganic Chemistry (specialization: X-ray structural analysis), Department of Inorganic Chemistry,
Faculty of Sciences, Charles University, Prague. |
| |
| Experience |
| 1997 (3 months) |
Postdoctoral fellow at ESRF Grenoble, ID 2 - High Brilliance Beam line (protein crystallography), Grenoble, Switzerland. |
| 1995-1996 |
Postdoctoral fellow at Laboratory of Structural Immunology, Institute Pasteur, Paris, France. |
| 1994 (3 months) |
Short-term fellowship at Laboratory of Structural Immunology, Institute Pasteur, Paris, France. |
| |
| Appointments |
| since 2008 |
Scientist, Structural biology research-service team, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of
the Czech Republic, Prague. |
| 1998-2008 |
Scientist, Department of Gene Manipulations, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague. |
| 1986-1989 |
Research assistant (X ray structure analysis of polycrystalic graphite like carbon materials), Institute of Geology, Czechoslovak Academy of Sciences, Prague. |
| |
| Teaching |
| since 2003 |
Determination of 3-D structures of macromolecules course: Department of Biochemistry, Faculty of Natural Sciences, Charles University, Prague. |
| since 2005 |
Structural biology: The Institute of Chemical Technology, Prague. |
| 2002-2008 |
Determination of 3-D structures of macromolecules course (part of Bioinformatics II lectures): Institute of Physical Biology, University of South Bohemia, České Budějovice. |
| 2001, 2002, 2003, 2005 |
Teaching at practical courses Crystallization course (CC2001, CC2002 and CC2003, CC2005): University and Academic Center Nové Hrady, Czech Republic. |
| 2004, 2006, 2008 |
Teaching at FEBS advanced courses: Advanced methods in protein crystallization, University and Academic Center Nové Hrady, Czech Republic. |
| |
| Research interest |
| Protein crystallography, phase problem, HIV protease, structure-assisted drug design, antibody fragments, metabolism of purines and pirimidines. |
