Organic Chemistry

Tutor	Dr. habil. Ullrich Jahn
Team	Ullrich Jahn
Topic	Approaches to the total synthesis of bioactive epidithiodiketopiperazine alkaloids
Faculty	FCHT / FPBT VŠCHT, PřF UK
Abstract	Epidithiodiketopiperazine alkaloids are fungal metabolits, which display wide ranging biological acitivity. Aim of the project is the development of short and high-yielding total syntheses of natural products, exemplified by gliotoxin and of analogs.