Intranet Čeština

LECTURE "Towards the pathological mechanisms of mitochondrial diseases"


Advent of Next generation sequencing represents big leap forward in diagnostics of rare diseases, including inherited mitochondrial dysfunctions. However, two challenges still remain – functional validation of candidate variants and production of model systems to understand the pathology associated with any particular mutated protein. On several recent cases we will demonstrate, how biochemists can still be relevant partners in the post-genome era.

© 2014 INSTITUTE OF PHYSIOLOGY CAS