Intranet Čeština

Computational Neuroscience

Computational Neuroscience

Main topics of research include:

 

Analysis of single-point stochastic neuronal models.

Main methodology is provided by mathematical modelling based on the theory of stochastic processes and differential equations, including extensive numerical simulations. Advanced statistical analysis of simulated as well as real experimental data is performed in order to estimate biophysically relevant parameters of the studied models.

 

Information processing in sensory neurons and neuronal models.

Methods of information theory and statistical estimation theory are applied to analyse the neuronal coding efficiency, based on both simulated and experimental data. Of particular interest is the notion of efficient coding hypothesis for insect olfactory sensory neurons, and biophysical modelling of ligand-receptor interaction in pheromone reception.

 

 

Organization of recent international conferences:

Publications

Šmít, Daniel - Fouquet, C. - Doulazmi, M. - Pincet, F. - Trembleau, A. - Zápotocký, Martin . BFPTool: a software tool for analysis of Biomembrane Force Probe experiments . BMC Biophysics. 2017, roč. 10, Feb, článku 2 . IF = 2.292 [ASEP] [ doi ]
Leváková, Marie - Tamborrino, M. - Košťál, Lubomír - Lánský, Petr . Accuracy of rate coding: When shorter time window and higher spontaneous activity help . Physical Review E. 2017, roč. 95, 2, článku 022310 . IF = 2.366 [ASEP] [ doi ]
Chakraborty, Soma - Kopecká, J. - Šprdlík, Otakar - Hoskovcová, M. - Ulmanová, O. - Růžička, E. - Zápotocký, Martin . Intermittent bilateral coherence in physiological and essential hand tremor . Clinical Neurophysiology. 2017, roč. 128, 4, p. 622-634 . IF = 3.866 [ASEP] [ doi ]
Košťál, Lubomír - Lánský, Petr . Coding accuracy on the psychophysical scale . Scientific Reports. 2016, roč. 6, Mar 29, p. 23810 . IF = 4.259 [ASEP] [ doi ]
Leváková, Marie - Tamborrino, M. - Košťál, Lubomír - Lánský, Petr . Presynaptic Spontaneous Activity Enhances the Accuracy of Latency Coding . Neural Computation. 2016, roč. 28, 10, p. 2162-2180 . IF = 1.760 [ASEP] [ doi ]
Košťál, Lubomír - Shinomoto, S. Efficient information transfer by Poisson neurons . Mathematical Biosciences and Engineering. 2016, roč. 13, 3, p. 509-520 . IF = 1.035 [ASEP] [ doi ]
Košťál, Lubomír . Stimulus reference frame and neural coding precision . Journal of Mathematical Psychology. 2016, roč. 71, Apr 2016, p. 22-27 . IF = 1.377 [ASEP] [ doi ]
Kortus, Štěpán - Srinivasan, Ch. - Forostyak, O. - Zápotocký, Martin - Ueta, Y. - Syková, E. - Chvátal, A. - Verkhratsky, A. - Dayanithi, G. Sodium-calcium exchanger and R-type Ca2+ channels mediate spontaneous [Ca2+](i) oscillations in magnocellular neurones of the rat supraoptic nucleus . Cell Calcium. 2016, roč. 59, 6, p. 289-298 . IF = 3.707 [ASEP] [ doi ]
Kortus, Štěpán - Srinivasan, Ch. - Forostyak, O. - Ueta, Y. - Syková, E. - Chvátal, A. - Zápotocký, Martin - Verkhratsky, A. - Dayanithi, G. Physiology of spontaneous [Ca2+](i) oscillations in the isolated vasopressin and oxytocin neurones of the rat supraoptic nucleus . Cell Calcium. 2016, roč. 59, 6, p. 280-288 . IF = 3.707 [ASEP] [ doi ]
Forostyak, O. - Forostyak, S. - Kortus, Štěpán - Syková, E. - Verkhratsky, A. - Dayanithi, G. Physiology of Ca2+ signalling in stem cells of different origins and differentiation stages . Cell Calcium. 2016, roč. 59, 2-3, p. 57-66 . IF = 3.707 [ASEP] [ doi ]

Contacts

Institute of Physiology AS CR, v.v.i.
Department of Computational Neuroscience

Vídeňská 1083
14220 Prague 4
Czech Republic
tel. +420 241 062 276
fax. +420 241 062 488
   

kostal@biomed.cas.cz

 

People

Mgr. Lubomír Košťál, Ph.D.
head of the department

RNDr. Martin Zápotocký, Ph.D.
deputy head of the department

 
Mgr. Ondřej Nováček
PhD student
 
Bc. Tomáš Bárta
student
 
Jindřich Kalvoda
technician
 

Libuše Müllerová
technician

 

 

Frequent visitors and collaborators:

 
 
 
 
 
 
 

 

 

 

Past members:

 
Čupera Jakub, Mgr., PhD.
 
 
Pilarski Stevan, PhD.
 
Šanda Pavel, Mgr., PhD.
 
Rajdl Kamil, Mgr., PhD.

 

© 2014 INSTITUTE OF PHYSIOLOGY CAS