The Department of Adipose Tissue Biology  is involved in extensive cooperation among excellent European laboratories in order to:

1. identify markers of healthy development (BIOCLAIMS project; 11 partners) and
2. describe mechanisms which could increase energy expenditure in adipose tissue and prevent fat accumulation in the body (DIABAT project; 20 partners).

Especially the DIABAT project corresponds with the long-term strategy of the Department (see Kopecky J et al. 1995 J. Clin. Invest. 96:2914-2923 and review Flachs P et al. 2013. BBA). Both projects involve dietary and pharmacological experiments on laboratory mice.To reach to goals of these proejcts , we use complex in vivo phenotyping of animals (including an indirect calorimetry system, hyperinsulinemic-euglycemic clamps, in vivo analysis of body composition, and behavioral tests), advanced analytical tools (metabolomic analysis and gene expression screens), and cell culture studies.