2014
Physical and Theoretical Chemistry
Chalupský J., Rokob T.A., Kurashige Y., Yanai T., Solomon E.I., Rulíšek L., Srnec M.:
Reactivity of the Binuclear Non-Heme Iron Active Site of Δ9 Desaturase Studied by Large-Scale Multireference Ab Initio Calculations.
Journal of the American Chemical Society 136: 15977-15991, 2014.
Pospíšil L., Bednárová L.*, Štěpánek P., Slavíček P., Vávra J., Hromadová M., Dlouhá H., Tarábek J., Teplý F.:
Intense Chiroptical Switching in a Dicationic Helicene-Like Derivative: Exploration of a Viologen-Type Redox Manifold of a Non-Racemic Helquat.
Journal of the American Chemical Society 136: 10826–10829, 2014.
Savolainen J., Uhlig F., Ahmed S., Hamm P., Jungwirth P.:
Direct observation of the collapse of the delocalized excess electron in water.
Nature Chemistry 6: 697-701, 2014.
Vazdar K., Kunetskiy R., Saame J., Kaupmees K., Leito I., Jahn U.:
Very Strong Organosuperbases Formed by Combining Imidazole and Guanidine Bases: Synthesis, Structure, and Basicity.
Angewandte Chemie International Edition 53: 1435-1438, 2014.
Analytical Chemistry, Spectroscopy and other analytical methods
Šebestík J., Bouř P.:
Observation of Paramagnetic Raman Optical Activity of Nitrogen Dioxide.
Angewandte Chemie International Edition 53: 9236-9239, 2014.
Buděšínský M., Vaněk V., Dračínský M., Pohl R., Poštová-Slavětínská L., Sychrovský V., Pícha J.:
Determination of the configuration in six-membered saturated heterocycles (N, P, S, Se) and their oxidation products using experimental and calculated NMR chemical shifts.
Tetrahedron 70: 3871-3886, 2014.
Růžička M., Čížková M., Jirásek M., Teplý F., Koval D., Kašička V.:
Study of deoxyribonucleic acid-ligand interactions by partial filling affinity capillary electrophoresis.
Journal of Chromatography A 1349: 116-121, 2014.
Medicinal and Organic Chemistry
Kafka F., Holan M., Hidasová D., Pohl R., Císařová I., Klepetářová B., Jahn U.:
Oxidative Catalysis Using the Stoichiometric Oxidant as a Reagent - An Efficient Strategy for Single-Electron Transfer-Induced Tandem Anion-Radical Reactions.
Angewandte Chemie International Edition 53: 9944-9948, 2014.
Opekar S., Pohl, R., Beran P., Rulíšek L., Beier P.:
Diethyl Fluoronitromethylphosphonate: Synthesis and Application in Nucleophilic Fluoroalkyl Additions.
Chemistry - A European Journal 20: 1453-1458, 2014.
Řehoř I., Macková H., Filippov S.K., Kucka J., Proks V., Šlegerová J., Turner S., Van Tendeloo G., Ledvina M., Hrubý M., Cígler P.:
Fluorescent Nanodiamonds with Bioorthogonally Reactive Protein-Resistant Polymeric Coatings.
ChemPlusChem 79: 21-24, 2014.
Vaníková Z., Hocek M.:
Polymerase Synthesis of Photocaged DNA Resistant against Cleavage by Restriction Endonucleases
Angewandte Chemie International Edition 53: 6734-6737, 2014.
Director’s honorary mention
Krečmerová M., Pohl R., Masojídková M., Balzarini J., Snoeck R., Andrei G.:
Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-aza-C: Chemistry and antiviral activity.
Bioorganic and Medicinal Chemistry 22: 2896-2906, 2014.
Biochemistry and Molecular Biology
Baumlová A., Chalupská D., Róźycki B., Jovic M., Wisniewski E., Klíma M., Dubánková A., Kloer D.P., Nencka R., Balla T., Bouřa E.:
The crystal structure of the phosphatidylinositol 4-kinase IIα.
EMBO reports 15: 1085-1092, 2014.
Čermáková K., Těšina P., Demeulemeester J., El Ashkar S., Méreau H., Schwaller J., Rezáčová P., Veverka V., De Rijck J.:
Validation and Structural Characterization of the LEDGF/p75-MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia.
Cancer Research 74: 5139-5151, 2014.
Jílková A., Horn M., Řezáčová P., Marešová L., Fajtová P., Brynda J., Vondrášek J., McKerrow J.H., Caffrey C.R., Mareš M.:
Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch.
Structure 22: 1786-1798, 2014.
Zoll S., Stanchev S., Began J., Škerle J., Lepšík M., Peclinovaká L., Majer P., Stříšovský K.:
Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures.
EMBO Journal 33: 2408-2421, 2014.
Interdisciplinary
Kožíšek M., Lepšík M., Grantz Šašková K., Brynda J., Konvalinka J., Řezáčová P.:
Thermodynamic and structural analysis of HIV protease resistance to darunavir – analysis of heavily mutated patient-derived HIV-1 proteases.
FEBS Journal 281: 1834-1847, 2014.
Snášel J., Nauš P., Dostál J., Hnízda A., Fanfrlík J., Brynda J., Bourderioux A., Dušek M., Dvořáková H., Stolaříková J., Zábranská H., Pohl R., Konečný P., Džubák P., Votruba I., Hajdúch M., Řezáčová P., Veverka V., Hocek M., Pichová I.:
Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(het)aryl-7-deazaadenine ribonucleosides
Journal of Medicinal Chemistry 57: 8268-8279, 2014.
Šimák O., Pachl P., Fábry M., Buděšínský M., Jandušík T., Hnízda A., Skleničková R., Petrová M., Veverka V., Řezáčová P., Brynda J., Rosenberg I.:
Conformationally constrained nucleoside phosphonic acids – potent inhibitors of human mitochondrial and cytosolic 5‘(3‘)-nucleosidases.
Organic & Biomolecular Chemistry 12:7971-7982, 2014.