INSTITUTE OF PHYSIOLOGY CAS

Correlation between resistance to obesity and lipid synthesis in adipose tissue Cold exposure induces lipid synthesis in white adipose tissue; the ability to induce this process correlates with differential resistance to obesity of various strains of laboratory mice. Propensity to obesity is partially dependent on the intristic metabolic properties adipose tissue.

Role of Plzf gene in regulation of metabolic and cardiac traits An important role of Plzf in regulation of metabolic and cardiac traits in the rat that suggests a crosstalk between cell cycle regulators, metabolism, cardiac hypertrophy and fibrosis.

Mitochondria´a role in heart damage due to myocardial infarction Ischemic heart disease is the leading cause of morbidity and mortality in the Western world.

TMEM70 disease Animal models of human mitochondrial diseases enable detailed insight into pathogenic mechanisms, from molecular to organismal levels.