RNDr. Michal Tichý, Ph.D.

e-mail: michal.tichy@uochb.cas.cz
phone: +420 220183343


Born 10. 10. 1984 in Brandýs nad Labem (Czech Republic).

Scientific CV:
2004-2007 undergraduate study, Charles University in Prague - Faculty of Science, Bc. S. degree - specialization clinical and toxicological analysis (supervisor RNDr. Jan Šarek, Ph.D.)
2007-2009 undergraduate study, Charles University in Prague - Faculty of Science, M. S. degree - specialization organic chemistry (supervisor RNDr. Jan Šarek, Ph.D.)
2009-2015 PhD study, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)
2015-2016 Postdoctoral stay, ETH Zürich (supervisor Prof. Dr. François Diederich)
since 2017 Postdoctoral stay, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic (supervisor Dr. M. Hocek)

Awards:
2009 Zentiva award for the best diploma thesis (2nd position)


List of publications:

4.	Bosáková, A.; Perlíková, P.; Tichý, M.; Pohl, R.; Hocek, M.: "6-Aryl-4-amino-pyrimido[4,5-b]indole 2'-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study" Bioorg. Med. Chem. 2016, 24, 4528 - 4535.
3.	Tichý, M.; Pohl, R.; Tloušťová, E.; Weber, J.; Bahador, G.; Lee, Y.-J.; Hocek, M.: "Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido [4,5-b]indole ribonucleosides" Bioorg. Med. Chem. 2013, 21, 5362–5372.
2.	Tichý, M.; Pohl, R.; Xu, H. Y.; Chen, Y.-L.; Yokokawa, F.; Shi, P.-Y.; Hocek, M.: "Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides" Bioorg. Med. Chem. 2012, 20, 6123–6133.
1.	Krasulová, J.; Hanus, R.; Kutalová, K.; Šobotník, J.; Sillam-Dusse`s, D.; Tichý, M.; Valterová, I.: "Chemistry and Anatomy of the Frontal Gland in Soldiers of the Sand Termite Psammotermes hybostoma" J. Chem. Ecol. 2012, 38, 557–565.