2016

Acikara O. B., Hošek J., Babula P., Cvačka J., Buděšínský M., Dračínský M., Iscan G. S., Kadlecová D., Ballová L., Šmejkal K.:
Turkish Scorzonera Species Extracts Attenuate Cytokine Secretion via Inhibition of NF-kappa B Activation, Showing Anti-Inflammatory Effect in Vitro.
Molecules 21(1): 43, 2016.

Fabre B., Pícha J., Vaněk V., Selicharová I., Chrudinová M., Collinsová M., Žáková L., Buděšínský M. , Jiráček J.:
Synthesis and Evaluation of a Library of Trifunctional Scaffold-Derived Compounds as Modulators of the Insulin Receptor.
ACS Combinatorial Science 18(12): 710-722, 2016.

Kasal A., Buděšínský M., Mareš P., Krištofíková Z., Leitao A. J., Sá e Melo M. L., Silva M. M. C.:
Neurosteroids: Can a 2alpha,3alpha-epoxy ring make up for the 3alpha-hydroxyl group?.
Steroids 105: 12-18, 2016.

Kostov O., Páv O., Buděšínský M., Liboska R., Šimák O., Petrová M., Novák P., Rosenberg I.:
4-Toluenesulfonyloxymethyl-(H)-phosphinate: A Reagent for the Introduction of O- and S-Methyl-(H)-phosphinate Moieties.
Organic Letters 18(11): 2704-2707, 2016.

Kvasnica M., Oklešťková J., Bazgier V., Rárová L., Kořínková P., Mikulík J., Buděšínský M., Béreš T., Berka K., Lu Q., Russinova E., Strnad M.:
Design, synthesis and biological activities of new brassinosteroid analogues with a phenyl group in the side chain.
Organic & Biomolecular Chemistry 14(37): 8691-8701, 2016.

Nešuta O., Hexnerová R., Buděšínský M., Slaninová J., Bednárová L., Hadravová R., Straka J., Veverka V., Čeřovský V.:
Antimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics.
Journal of Natural Products 79(4): 1073-1083, 2016.

Viková J., Collinsová M., Kletvíková E., Buděšínský M., Kaplan V., Žáková L., Veverka V., Hexnerová R., Tarazona A. R. J., Straková J., Selicharová I., Vaněk V., Wright D. W., Watson C. J., Turkenburg J. P., Brzozowski A. M., Jiráček J.:
Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Scientific Reports 6: 19431, 2016.

Břehová P., Šmídková M., Skácel J., Dračínský M., Mertlíková-Kaiserová H., Velasquez M. P. S., Watts V. J., Janeba Z.:
Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.
ChemMedChem 11(22): 2534-2546, 2016.

Dračínský M., Šála M., Klepetářová B., Šebera J., Fukal J., Holečková V., Tanaka Y., Nencka R., Sychrovský V.:
Benchmark Theoretical and Experimental Study on N-15 NMR Shifts of Oxidatively Damaged Guanine.
Journal of Physical Chemistry B 120(5): 915-925, 2016.

Dračínský M., Bouř P., Hodgkinson P.:
Temperature Dependence of NMR Parameters Calculated from Path Integral Molecular Dynamics Simulations.
Journal of Chemical Theory and Computation 12(3): 968-973, 2016.

Galeta J., Šála M., Dračínský M., Vrábel M., Havlas Z., Nencka R.:
Single-Step Formation of Pyrimido[4,5-d]pyridazines by a Pyrimidine-Tetrazine Tandem Reaction.
Organic Letters 18(15): 3594-3597, 2016.

Horník Š., Červenková Šťastná L., Cuřínová P., Sýkora J., Káňová K., Hrstka R., Císařová I., Dračínský M., Karban J.:
Synthesis and in Vitro Cytotoxicity of Acetylated 3-Fluoro,4-Fluoro and 3,4-Difluoro Analogs of D-glucosamine and D-galactosamine.
Beilstein Journal of Organic Chemistry 12: 750-759, 2016.

Kaiser M. M., Poštová Slavětínská L., Dračínský M., Lee Y. J., Tian Y., Janeba Z.:
Synthesis and biological properties of prodrugs of (S)-3-(adenin-9-yl)-2-(phosphonomethoxy)propanoic acid.
European Journal of Medicinal Chemistry 108: 374-380, 2016.

Procházková E., Čechová L., Tarábek J., Janeba Z., Dračínský M.:
Tunable Push-Pull Interactions in 5-Nitrosopyrimidines.
Journal of Organic Chemistry 81(9): 3780-3789, 2016.

Řehová L., Dračínský M., Jahn U.:
A general approach to iridoids by applying a new Julia olefination and a tandem anion-radical-carbocation crossover reaction.
Organic & Biomolecular Chemistry 14(40): 9612-9621, 2016.

Wu T., Průša J., Kessler J., Dračínský M., Valenta J., Bouř P.:
Detection of Sugars via Chirality Induced in Europium(III) Compounds.
Analytical Chemistry 88(17): 8878-8885, 2016.

Amatov T., Gebauer M., Pohl R., Císařová I., Jahn U.:
Oxidative radical cyclizations of diketopiperazines bearing an amidomalonate unit. Heterointermediate reaction sequences toward the asperparalines and stephacidins.
Free Radical Research 50: 6-17, 2016.

Bosáková A., Perlíková P., Tichý M., Pohl R., Hocek M.:
6-Aryl-4-amino-pyrimido[4,5-b]indole 2'-deoxyribonucleoside triphosphates (benzo-fused 7-deaza-dATP analogues): Synthesis, fluorescent properties, enzymatic incorporation into DNA and DNA-protein binding study.
Bioorganic & Medicinal Chemistry 24(19): 4528-4535, 2016.

Botha F., Slavíčková M., Pohl R., Hocek M.:
Copper-mediated arylsulfanylations and arylselanylations of pyrimidine or 7-deazapurine nucleosides and nucleotides.
Organic & Biomolecular Chemistry 14(42): 10018-10022, 2016.

Coe B. J., Rusanova D., Joshi V., Sánchez S., Vávra J., Khobragade D., Severa L., Císařová I., Šaman D., Pohl R., Clays K., Depotter G., Brunschwig B. S., Teplý F.:
Helquat Dyes: Helicene-like Push-Pull Systems with Large Second-Order Nonlinear Optical Responses.
Journal of Organic Chemistry 81(5): 1912-1920, 2016.

Dziuba D., Pospíšil P., Matyašovský J., Brynda J., Nachtigallová D., Rulíšek L., Pohl R., Hof M., Hocek M.:
Solvatochromic fluorene-linked nucleoside and DNA as color-changing fluorescent probes for sensing interactions.
Chemical Science 7(9): 5775-5785, 2016.

Choi J. W., Synytsya A., Capek P., Bleha R., Pohl R., Park Y. I.:
Structural analysis and anti-obesity effect of a pectic polysaccharide isolated from Korean mulberry fruit Oddi (Morus alba L.).
Carbohydrate Polymers 146: 187-196, 2016.

Kafka F., Pohl R., Císařová I., Mackman R., Bahador G., Jahn U.:
N,2,3,4-Tetrasubstituted Pyrrolidines through Tandem Lithium Amide Conjugate Addition/Radical Cyclization/Oxygenation Reactions.
European Journal of Organic Chemistry 2016(22): 3862-3871, 2016.

Kielkowski P., Cahová H., Pohl R., Hocek M.:
Flexible double-headed cytosine-linked 2'-deoxycytidine nucleotides. Synthesis, polymerase incorporation to DNA and interaction with DNA methyltransferases.
Bioorganic & Medicinal Chemistry 24(6): 1268-1276, 2016.

Klívar J., Jančařík A., Šaman D., Pohl R., Fiedler P., Bednárová L., Starý I., Stará I. G.:
[2++2+2] Cycloisomerisation of Aromatic Cyanodiynes in the Synthesis of Pyridohelicenes and Their Analogues.
Chemistry - A European Journal 22(40): 14401-14405, 2016.

Matyašovský J., Perlíková P., Malnuit V., Pohl R., Hocek M.:
2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove.
Angewandte Chemie - International Edition 55(51): 15856-15859, 2016.

Miggiano R., Perugino G., Ciaramella M., Serpe M., Rejman D., Páv O., Pohl R., Garavaglia S., Lahiri S., Rizzi M., Rossi F.:
Crystal structure of Mycobacterium tuberculosis O-6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA.
Biochemical Journal 473(2): 123-133, 2016.

Olszewska A., Pohl R., Brázdová M., Fojta M., Hocek M.:
Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins.
Bioconjugate Chemistry 27(9): 2089-2094, 2016.

Pomeisl K., Beier P., Pohl R., Krečmerová M.:
Novel and Efficient Synthesis of gem-Difluorinated Derivatives of Acyclic Nucleoside Phosphonates (ANPs).
ChemistrySelect 1(10): 2102-2106, 2016.

Reyes G., Paul E., Kapal T., Klepetářová B., Šaman D., Pohl R., Zawada Z., Kužmová E., Hájek M., Teplý F.:
Structural revisions of small molecules reported to cross-link G-quadruplex DNA in vivo reveal a repetitive assignment error in the literature.
Scientific Reports 6: 23499, 2016.

Slavíčková M., Pohl R., Hocek M.:
Additions of Thiols to 7-Vinyl-7-deazaadenine Nucleosides and Nucleotides. Synthesis of Hydrophobic Derivatives of 2'-Deoxyadenosine, dATP and DNA.
Journal of Organic Chemistry 81(22): 11115-11125, 2016.

Štěpánek P., Cowie T. Y., Šafařík M., Šebestík J., Pohl R., Bouř P.:
Resolving Electronic Transitions in Synthetic Fluorescent Protein Chromophores by Magnetic Circular Dichroism.
ChemPhysChem 17(15): 2348-2354, 2016.

Chukwujekwu J. C., Rengasamy K.R.R., de Kock C. A., Smith P. J., Poštová Slavětínská L., van Staden J.:
Alpha-glucosidase inhibitory and antiplasmodial properties of terpenoids from the leaves of Buddleja saligna Willd.
Journal of Enzyme Inhibition and Medicinal Chemistry 31(1): 63-66, 2016.

Perlíková P., Rylová G., Nauš P., Elbert T., Tloušťová E., Bourderioux A., Poštová Slavětínská L., Motyka K., Doležal D., Znojek P., Nová A., Harvanová M., Džubák P., Šiller M., Hlaváč J., Hajdúch M., Hocek M.:
7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action.
Molecular Cancer Therapeutics 15(5): 922-937, 2016.

Sabat N., Poštová Slavětínská L., Klepetářová B., Hocek M.:
C-H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7-and 9-Deazapurine-8-phosphonate Derivatives.
Journal of Organic Chemistry 81(19): 9507-9514, 2016.

Sabat N., Nauš P., Matyašovský J., Dziuba D., Poštová Slavětínská L., Hocek M.:
Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki-Miyaura Cross-Coupling Reactions.
Synthesis 48(7): 1029-1045, 2016.

Procházková E., Kolmer A., Ilgen J., Schwab M., Kaltschnee L., Fredersdorf M., Schmidts V., Wende R. C., Schreiner P. R., Thiele C. M.:
Uncovering Key Structural Features of an Enantioselective Peptide-Catalyzed Acylation Utilizing Advanced NMR Techniques.
Angewandte Chemie - International Edition 55(51): 15754-15759, 2016.

Šála M., Kögler M., Plačková P., Mejdrová I., Hřebabecký H., Procházková E., Strunin D., Lee G., Birkuš G., Weber J., Mertlíková-Kaiserová H., Nencka R.:
Purine analogs as phosphatidylinositol 4-kinase III beta inhibitors.
Bioorganic and Medicinal Chemistry Letters 26(11): 2706-2712, 2016.

Bildziukevich U., Kaletová E., Šaman D., Sievänen, Kolehmainen E.T., Šlouf M., Wimmer Z.:
Spectral and microscopic study of self-assembly of novel cationic spermine amides of betulinic acid.
Steroids 117: 90-96, 2016.

Šimon P., Baszczyňski O., Šaman D., Stepan G., Hu E., Lansdon E. B., Jansa P., Janeba Z.:
Novel (2,6-difluorophenyl)(2-(phenylamino)pyrimidin-4-yl) methanones with restricted conformation as potent non-nucleoside reverse transcriptase inhibitors against HIV-1.
European Journal of Medicinal Chemistry 122: 185-195, 2016.

Vlk M., Mičolová P., Urban M., Kvasnica M., Šaman D., Šarek J.:
N-15-labelled pyrazines of triterpenic acids.
Journal of Radioanalytical and Nuclear Chemistry 308(2): 733-739, 2016.

Wimmerová M., Siglerová V., Šaman D., Šlouf M., Kaletová E., Wimmer Z.:
Improved enzyme-mediated synthesis and supramolecular self-assembly of naturally occurring conjugates of b-sitosterol.
Steroids 117: 38-43, 2016.

Bajzíková A., Kohout M., Tarábek J., Svoboda J., Novotná V., Vejpravová J., Pociecha D., Gorecka E.:
All-organic liquid crystalline radicals with a spin unit in the outer position of a bent-core system.
Journal of Materials Chemistry C 4(48): 11540-11547, 2016.

Navrátil R., Tarábek J., Linhart I., Martinů T.:
Radical and Nitrenoid Reactivity of 3-Halo-3-phenyldiazirines.
Organic Letters 18(15): 3734-3737, 2016.

Sokolová R., Tarábek J., Papoušková B., Kocábová J., Fiedler J., Vacek J., Marhol P., Vavříková E., Křen V.:
Oxidation of the Flavonolignan Silybin. in situ EPR Evidence of the Spin-Trapped Silybin Radical.
Electrochimica acta 205: 118-123, 2016.