Papers


Siegl S., Dzijak R., Vazquez A., Pohl R., Vrabel M.:
The Discovery of Pyridinium 1,2,4-Triazines with Enhanced Performance in Bioconjugation Reactions.
Chemical Science 8: 3593–3598, 2017.

Vazquez A., Dzijak R., Dracinsky M., Rampmaier R., Siegl S.J., Vrabel M.:
Mechanism-Based Fluorogenic trans-Cyclooctene—Tetrazine Cycloaddition.
Angewandte Chemie International Edition 56: 1334-1337, 2017.

Galeta J., Sala M., Dracinsky M., Vrabel M., Havlas Z., Nencka R.:
Single-Step Formation of Pyrimido[4,5-d]pyridazines by a Pyrimidine-Tetrazine Tandem Reaction.
Organic Letters 18: 3594-3597, 2016.

Carell T., Vrabel M.:
Bioorthogonal Chemistry-Introduction and Overview.
Topics in Current Chemistry 374/1, ISSN: 2365-0869, eISSN: 2364-8961, 2016.

Datz S., Argyo C., Gattner M., Weiss V., Brunner K., Bretzler J., von Schirnding C., Torrano A.A., Spada F., Vrabel M., Engelke H., Bräuchle C., Carell T., Bein T.:
Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release.
Nanoscale 8: 8101-8110, 2016.

Dadova J., Vrabel M., Adamik M., Brazdova M., Pohl R., Fojta M., Hocek M.:
Azidopropylsulfonamide as a new bifunctional click reagent for bioorthogonal conjugations: Application for DNA-Protein Cross-Linking.
Chemistry – A European Journal 21: 16091-16102, 2015.

Schiesser S., Hackner B., Vrábel M., Beck W., Carell T.:
Synthesis and DNA-Damaging Properties of Cisplatin-N-Mustard Conjugates.
European Journal of Organic Chemistry 2654-2660, 2015.

Ehrlich M., Gattner M.J., Viverge B., Bretzler J., Eisen D., Stadlmeier M., Vrábel M., Carell T.:
Orchestrating the biosynthesis of an unnatural pyrrolysine amino Acid for its direct incorporation into proteins inside living cells.
Chemistry - A European Journal 21: 7701-7704, 2015.

Gattner M.J., Ehrlich M., Vrabel M.:
Sulfonyl azide-mediated norbornene aziridination for orthogonal peptide and protein labeling.
Chemical Communications 50: 12568-12571, 2014.

Flügel V., Vrabel M., Schneider S.:
Structural basis for the site specific incorporation of lysine derivatives into proteins.
PLoS One 9: e96198, 2014.

Vrabel M., Kölle P., Brunner K.M., Gattner M.J., López-Carillo V., de Vivie-Riedle R., Carell T.:
Norbornenes in inverse electron-demand Diels-Alder reactions.
Chemistry - A European Journal 19: 13309-13312, 2013.

Schneider S., Gattner M.J., Vrabel M., Flügel V., López-Carrillo V., Prill S., Carell T.:
Structural Insights into Incorporation of Norbornene Amino Acids for Click Modification of Proteins.
ChemBioChem 14: 2114-2118, 2013.

Gattner M.J., Vrabel M., Carell T.:
Synthesis of ε-N-propionyl-, ε-N-butyryl-, and ε-N-crotonyl-lysine containing histone H3 using the pyrrolysine system.
Chemical Communications 49: 379-381, 2013.

Kaya E., Vrabel M., Deiml C., Prill S., Fluxa V.S., Carell T.:
Genetically encoded norbornene amino acid for the mild and selective modification of proteins in a copper-free click reaction.
Angewandte Chemie International Edition 51: 4466-4469, 2012.

Kaya E., Gutsmiedl K., Vrabel M., Mueller M., Thumbs P., Carell T.:
Synthesis of threefold glycosilated proteins using click chemistry and genetically encoded unnatural amino acids.
ChemBioChem 10: 2858-2861, 2009.