INSTITUTE OF PHYSIOLOGY CAS

Axon zippering and its control by tension forces Axon bundling plays an important role in the formation of brain circuits and peripheral nerves. This dynamical process is regulated by the competition of adhesive forces and mechanical tension in the axons.

Cellular and molecular basis of memory Recently, experimental work has focused on understanding molecular and cellular basis of memory. Results show that memory is associated with long-term changes in the efficacy of synaptic transmission at glutamatergic synapses.

Correlation between resistance to obesity and lipid synthesis in adipose tissue Cold exposure induces lipid synthesis in white adipose tissue; the ability to induce this process correlates with differential resistance to obesity of various strains of laboratory mice. Propensity to obesity is partially dependent on the intristic metabolic properties adipose tissue.

Role of Plzf gene in regulation of metabolic and cardiac traits An important role of Plzf in regulation of metabolic and cardiac traits in the rat that suggests a crosstalk between cell cycle regulators, metabolism, cardiac hypertrophy and fibrosis.