Papers

Schimer J., Pávová M., Anders M., Pachl P., Šácha P., Cígler P., Weber J., Majer P., Řezáčová P., Krausslich H.G., Muller B., Konvalinka J.:
Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor.
Nature Communications 6: 6461, 2015.

Mejdrová I., Chalupská D., Kögler M., Šála M., Plačková P., Baumlová A., Hřebabecký H., Procházková E., Dejmek M., Guillon R., Strunin D., Weber J., Lee G., Birkus G., Mertlíková-Kaiserová H., Bouřa E., Nencka R.:
Highly Selective Phosphatidylinositol 4-Kinase IIIß Inhibitors and Structural Insight into Their Mode of Action.
Journal of Medicinal Chemistry 58: 3767-3793, 2015.

Nauš P., Caletková O., Perlíková P., Poštová Slavětínská L., Tloušťová E., Hodek J., Weber J., Džubák P., Hajdúch M., Hocek M.:
Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides.
Bioorganic & Medicinal Chemistry 23: 7422–7438, 2015.

Barešová P., Musilová J., Pitha P.M., Lubyová B.:
p53 tumor suppressor protein stability and transcriptional activity are targeted by Kaposi's sarcoma-associated herpesvirus-encoded viral interferon regulatory factor 3.
Molecular and Cellular Biology 34: 386-899, 2014.

Gibson R.M., Weber J., Winner D., Miller M.D., Quinones-Mateu M.E.:
Contribution of human immunodeficiency virus type 1 minority variants to reduced drug susceptibility in patients on an integrase strand transfer inhibitor-based therapy.
PLoS ONE 9: e104512, 2014.

Jagtap P.R., Ford L., Deister E., Pohl R., Císařová I., Hodek J., Weber J., Mackman R., Bahador G., Jahn U.:
Highly functionalized and potent antiviral cyclopentane derivatives formed by a tandem process consisting of organometallic, transition-metal-catalyzed, and radical reaction. steps.
Chemistry 20: 10298-10304, 2014.

Tichý M., Pohl R., Tloušťová E., Weber J., Bahador G., Lee Y.J., Hocek M.:
Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides.
Bioorganic & Medicinal Chemistry 21: 5362-5372, 2013.

Weber J., Rose J.D., Vazquez A.C., Winner, D., Margot N., McColl D.J., Olivo P.D., Miller M.D., Quinones-Mateu M.E.:
Resistance Mutations Outside the Integrase Coding Region Have an Effect on Human Immunodeficiency Virus Replicative Fitness But Do Not Affect Its Susceptibility to Integrase Strand Transfer Inhibitors.
PLoS ONE 8: e65631, 2013.

Weber J., Vazquez A., Winner D., Gibson R., Rhea A., Rose J., Wylie D., Henry K., Wright A., King K., Archer J., Poveda E., Soriano V., Robertson D., Olivo P., Arts E., Quinones-Mateu M.E.:
Sensitive Cell-based Assay to Determine Human Immunodeficiency Virus Type 1 Coreceptor Tropism.
Journal of Clinical Microbiology 51: 1517-1527, 2013.

Archer J., Weber J., Henry K., Winner D., Gibson R., Lee L., Paxinos E., Arts E.J., Robertson D.L., Mimms L., Quinones-Mateu M.E.
Use of Four Next-Generation Sequencing Platforms to Determine HIV-1 Coreceptor Tropism.
PLoS ONE 7: e49602, 2012.