LC-MS systémy


LCQ Fleet

Location:   Department of Mass Spectrometry
Responsible person:   Dr. Josef Cvačka (phone 220 183 303)

LCQ Fleet


LCQ Fleet (Thermo Fisher Scientific) is a 3D ion trap mass spectrometer capable of multiple stage (MSn) analyses. The instrument has an atmospheric pressure ionization source that supports ESI and APCI probes. The optimal mass range of the spectra is 50 - 2000 Da. LCQ Fleet can be coupled to HPLC system for LC/MS applications. Applications include clinical and forensic toxicology, natural product analysis, impurity analysis, metabolite profiling and general analytical chemistry. This instrument was installed in February 2008.


Waters UPLC-MS Acquity

Location:   Research team of Dr. Jiří Šrogl
Responsible person:   Dr. Svatava Voltrová (phone 220 183 392)

Waters UPLC-MS Acquity


The Waters UPLC-MS Acquity combines good resolution, sensitivity, and speed of UltraPerformance technology with single quadrupole MS detection. Rapid polarity switching and multi-mode ionization with simultaneous APCI and ESI for comprehensive compound analyses in a single injection, with ESCiTechnology. Control and data acquisition with MassLynx Software.


HPLC System Waters with Micromass ZQ MS detector

Location:   Research team of Dr. Ivo Starý
Responsible person:   Dr. Jiří Rybáček (phone 220 183 226)

HPLC System Waters with Micromass ZQ MS detector


This state-of-art HPLC-MS System Waters comprises Waters 515 HPLC pump, Knauer HPLC pump, Waters Micromass ZQ MS detector, Waters 2487 Dual λ absorbance system, Waters 2525 binary gradient module, Waters 2420 ELS detector, Waters 2267 sample manager and Water column fluidics organiser.


LC-MS System Waters

Location:   Research team of Dr. Ivan Rosenberg
Responsible person:   Dr. Ivan Rosenberg

LC-MS System Waters


Standard LC-MS system for analytical/semipreparative work comprises Waters 515 HPLC pump, Waters Micromass ZQ MS detector, Waters 600 controller, Waters 2998 photodiode array (PDA) detector and Waters sample manager.


LC-MS System Waters Alliance

Location:   Biochemical Pharmacology of Antimetabolites (Dr. Helena Mertlíková-Kaiserová)
Responsible person:   Dr. Helena Mertlíková-Kaiserová (phone 220 183 114)

LC-MS System Waters


LC-MS system for analytical/semipreparative work comprises Waters 2795 separations module, Waters Micromass ZQ MS detector, Waters 2475 mullti fluorescence detector and Waters 2996 photodiode array (PDA) detector.


Agilent 6230 Accurate-Mass TOF LC/MS

Location:   Medicinal Chemistry (Dr. Pavel Majer)
Responsible person:   Radko Souček (phone 220 183 354)

Agilent 6230 Accurate-Mass TOF LC/MS


The Agilent 6230 Accurate-Mass TOFMS system features Agilent Jet Stream Thermal Focusing technology for significantly improved sensitivity, as well as enhanced MassHunter Workstation software for superior data mining and analysis capabilities. These new features, coupled with Agilent’s True High-Definition TOF technology, enable the 6230 Accurate-Mass TOF to deliver exceptional sensitivity, excellent mass accuracy, fast data acquisition, and streamlined qualitative and quantitative analysis. An Agilent 1260 Infinity Binary LC is coupled with this 6230 Accurate-Mass TOFMS system for on-line HPLC-HR-ESI/APCI-MS analysis. Typical sample types suitable for analysis on the Agilent 6230 LC-TOFMS include synthetic organic molecules, synthetic peptides, natural products, and proteins.


Thermo Scientific UltiMate 3000 coupled with Finnigan LCQ Deca MS

Location:   Infochemicals (Dr. Irena Valterová)
Responsible person:   Dr. Edita Kofroňová (phone 220 183 281)

Thermo Scientific Dionex UltiMate 3000 coupled with Finnigan LCQ Deca MS


The Thermo Scientific Dionex UltiMate 3000 LC system provides the right solution for demanding microbore, analytical, and semipreparative LC applications. The Finnigan LCQ DECA is an ultra-sensitive, ion trap LC mass spectrometer built upon the proven reliability of the company's classic LCQ. It provides high sensitivity and specificity among LC/MSn analytical instruments for research applications.


Shimadzu LCMS-2020 LC-MS system

Location:   Research team of Dr. Milan Vrábel
Responsible person:   Eva Zborníková (phone 220 183 379)

Shimadzu LCMS-2020


Analytical to semipreparative LC-MS system Shimadzu LCMS-2020 that comprises three Shimadzu LC-20AD pumps, SIL-20A HT autosampler, Shimadzu SPD-M20A PDA detector and LCMS-2020 Single Quadrupole Liquid Chromatograph Mass Spectrometer with ESI ionization (Mass range: 10 - 2000 m/z, Scanning speed: 15 000 u/s, Polarity switching: 15 msec).