Laboratoř růstových regulátorů
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and Institute of Experimental Botany, Academy of Sciences of the Czech Republic (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Pracovníci
vedoucí skupinyvedoucí vědecký pracovník
- Prof. ing. Miroslav Strnad CSc.
vedoucí vědecký pracovník
vědecký pracovník
- RNDr. Martin Fellner Ph.D.
- Jiří Grúz
- Doc., Ing. Jan Krekule DrSc.
- Doc. RNDr. Vladimír Kryštof Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- Mgr. Ondřej Novák Ph.D.
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Mgr. Lucie Plíhalová Ph.D.
- Jiří Pospíšil
- Jitka Široká
- Mgr. Danuše Tarkowská Ph.D.
- Jiří Voller
vědecký asistent
- Michaela Mrvková
- Mgr. Lukáš Spíchal Ph.D.
odborný pracovník
sekretářka-asistentka
- Jitka Hansgutová DiS.
postdoktorand
doktorand
údržba
Výzkumné projekty
Publikace
2017
- PLANT PHYSIOLOGY 173 552-565 2017 (External fulltext)
- ANNALS OF BOTANY 119 151-166 2017 Fulltext: PDF link pouze na intranetu
- PLoS ONE 12 e0170715 2017 (External fulltext)
2016
- EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 110 291-301 2016 Fulltext: veřejný PDF odkaz
- PLANT PHYSIOLOGY 172 874–888 2016 (External fulltext)
- PROCEEDINGS OF THE NAS OF THE USA 113 11016-11021 2016 Fulltext: veřejný PDF odkaz
2015
- MOLECULAR CELL 57 984-994 2015 Fulltext: veřejný PDF odkaz
- PNAS 112 291-296 2015 Fulltext: veřejný PDF odkaz
- PLANT CELL 27 1955-1967 2015 Fulltext: veřejný PDF odkaz
- PLoS ONE 10 (2) e0117793 2015 (External fulltext)