HomePhD Study at IOCBArchive - 2013Organic Chemistry

Organic Chemistry

Tutor Mgr. Petr Cígler, Ph.D.
Team Petr Cígler
Topic Fluorescent diamonds nanosensors
Faculty PřF UK, VŠCHT
Abstract

Fluorescent nanodiamonds are unique probes exhibiting high quantum yields and extremely stable fluorescence. They represent new and undeveloped platform for sensor and biosensor construction. Fluorescence of nanodiamonds is caused by presence of local defects, NV-centers, in crystal lattice.  This type of fluorescence can be affected by change in charge density close to diamond surface. Thus new type of sensor originates when molecules that can change their charge if exposed to analyte are anchored to diamond surface. Nanodiamonds surface can be decorated by various types of conjugation protocols. 

Ph.D. thesis will be focused on:
• Preparation of monodisperse fluorescent nanodiamonds from polydisperse materials
• Investigation of new methods for increasing fluorescence of nanodiamonds
• Analysis of spatial distribution of NV-centers in nanodiamonds
• Development of sensors having fluorescent NV-centers in nanodiamonds for detection of biologically important analytes.