Lidé

Jméno Špaček Petr
Pozice Postdoktorand
Petr Špaček

Petr Špaček, Ph.D.

Postdoctoral fellow


Targeted Analogs of Nucleic Acid Components - Dr. Zlatko Janeba Senior Research Group
Institute of Organic Chemistry and Biochemistry CAS, v.v.i.
Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

☎: (+420) 220 183 109

 
Education
2009-2017 Ph.D. in organic chemistry, under supervision of Dana Hocková, Ph.D., Institute of Chemical Technology (ICT), Prague and Institute of Organic Chemistry and Biochemistry CAS, Prague. University of Chemistry and Technology, Prague (UCT Prague) & Institute of Organic Chemistry and Biochemistry (IOCB), Czech Academy of Sciences, Prague (in the Group of Prof. Antonín Holý and after his retirement in the Group of Dr. Zlatko Janeba)
2007-2009 M.Sc. (Ing.) in organic chemistry, under Prof. Jiří Svoboda, Department of Organic Chemistry, Faculty of Chemical Technology, ICT Prague.
2003-2007 B.Sc. in organic chemistry at Department of Organic Chemistry, Faculty of Chemical Technology, ICT Prague.
 
Experience
2006-2009 Research project in chemistry of liquid crystals (Supervisor: Prof. Jiří Svoboda).
2008 (3 weeks) Research and Development - Interpharma, Prague, Czech Republic.
 
Appointments
since 2010 Department of Targeted Analogues of Nucleic Acid Components, Institute of Organic Chemistry and Biochemistry (IOCB), Czech Academy of Sciences, Prague (Group of Dr. Zlatko Janeba), international collaboration (The University of Queensland and Australian Army Malaria Institute) and domestic collaboration (Military Health Institute, Biological Defence Department at Těchonín; Laboratory of Functional Biology of Protists, Institute of Parasitology, Biology Centre CAS).
- Collaborative international research project on medicinal chemistry of acyclic nucleoside phosphonates as inhibitors of 6-oxopurine phosphoribosyl transfarases.
- Collaborative research project on medicinal chemistry of adenylate cyclase inhibitors.
2009-2010 Department of Chemistry and Biochemistry of Nucleic Acid Components (head Prof. Antonín Holý) IOCB CAS; Synthesis of acyclic nucleoside phosphonates.
2006-2009 Department of Organic Chemistry, Group of heterocyclic and material chemistry (head Prof. Jiří Svoboda), UCT Prague; Synthesis of shaped liquid crystals.
 
Awards
2006 Students' conference (Organic chemistry), Faculty of Chemical Technology ICT Prague; (2nd position).
2007 Students' conference (Organic chemistry), Faculty of Chemical Technology ICT Prague; (3rd position).
 
Research interest
Main expertise covering the areas of organic chemistry and synthesis, drug design, structure-activity relationship studies. Previous work was focused mainly on synthesis of analogues of nucleosides, acyclic nucleoside phosponates as enzyme inhibors and prodrugs. Passionate interest in heterocyclic chemistry, chemistry of biologically active substances, natural products.