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Education |
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1987-1991 |
Graduate studies in the Institute of OrganicChemistry and Biochemistry, Czechoslovak Academy of Science, Prague, Czechoslovakia (Ph.D.). |
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1981-1986 |
Graduated in biochemistry at the Faculty of Science, Charles University, Prague, Czechoslovakia (Master). |
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Appointments |
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2003 |
Assistant Professor ("habilitation") at the Department of Biochemistry, Faculty of Natural Sciences, Charles University, Prague. |
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1996 |
Lecturer at the Department of Biochemistry, Faculty of Natural Sciences, Charles University, Prague. |
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1997 |
Senior scientist at the Institute of Organic Chemistry and Biochemistry, ASCR, Prague. |
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1991 |
Research fellow at the Institute of Organic Chemistry and Biochemistry, CASCR, Prague. |
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Experience |
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1997 (6 months) |
Research stay at Heinrich Pette Institut, University of Hamburg, Germany: biochemistry of retroviruses. |
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1991, 1993-1994 |
Research stay as FEBS (5 months) and Alexander von Humboldt Foundation fellow (18 months) in the laboratory of Dr. Hans-Georg Kraeusslich, German Cancer Research Center, Heidelberg: biochemistry of retroviruses. |
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1990, 1991 |
Prof. John Kay, Department of Biochemistry, Cardiff University, Cardiff; substrate specificity of HIV-1 protease. |
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Awards |
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2003 |
Elected full member of the Learned Society of the Czech Republic. |
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2003 |
Research Prize from the Ministry of Health of the Czech Republic. |
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2002 |
Otto Wichterle Premium (Czech Academy of Science). |
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1997 |
Prize of the Learned Society of the Czech Republic. |
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1995-2001 |
Howard Hughes Medical Institute, International Research Program Scholar. |
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1993-1994, 1997 |
Alexander von Humboldt fellowship. |
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1992 |
FEBS travel fellowship. |
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1992 |
Short term fellowship from Federation of European Biochemical Societies (FEBS). |
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1991 |
Short term fellowship from Deutsches Forschungsgemeinschaft. |
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Memberships |
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Member of scientific advisory boards of Institute of Molecular Genetics, Prague, Institute of Organic Chemistry and Biochemistry, Prague and Masaryk University, Brno. |
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Papers and Citations |
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56 papers in peer-reviewed international journals, 1031 citation (as of March, 2007) according to SCI. |
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Main research interests |
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Substrate specificity of retroviral proteases; rational design of HIV protease inhibitors; viral resistance development; biology and biochemistry of neuropeptidases. |
