Papers
Siegl S.J., Vrábel M.:
Probing the scope of the amidine-1,2,3-triazine cycloaddition as a prospective click ligation method.
European Journal of Organic Chemistry, published online on April 26, 2018.
Siegl S.J., Vázquez A., Dzijak R., Dračínský M., Galeta J., Rampmaier R., Klepetářová B., Vrábel M.:
Design and Synthesis of aza-Bicyclononene Dienophiles for Rapid Fluorogenic Ligations.
Chemistry a European Journal 24: 2426-2432, 2018.
Siegl S., Dzijak R., Vazquez A., Pohl R., Vrábel M.:
The Discovery of Pyridinium 1,2,4-Triazines with Enhanced Performance in Bioconjugation Reactions.
Chemical Science 8: 3593–3598, 2017.
Vazquez A., Dzijak R., Dracinsky M., Rampmaier R., Siegl S.J., Vrábel M.:
Mechanism-Based Fluorogenic trans-Cyclooctene—Tetrazine Cycloaddition.
Angewandte Chemie International Edition 56: 1334-1337, 2017.
Galeta J., Šála M., Dračínský M., Vrábel M., Havlas Z., Nencka R.:
Single-Step Formation of Pyrimido[4,5-d]pyridazines by a Pyrimidine-Tetrazine Tandem Reaction.
Organic Letters 18: 3594-3597, 2016.
Carell T., Vrabel M.:
Bioorthogonal Chemistry-Introduction and Overview.
Topics in Current Chemistry 374/1, ISSN: 2365-0869, eISSN: 2364-8961, 2016.
Datz S., Argyo C., Gattner M., Weiss V., Brunner K., Bretzler J., von Schirnding C., Torrano A.A., Spada F., Vrábel M., Engelke H., Bräuchle C., Carell T., Bein T.:
Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release.
Nanoscale 8: 8101-8110, 2016.
Dadová J., Vrábel M., Adamik M., Brázdová M., Pohl R., Fojta M., Hocek M.:
Azidopropylsulfonamide as a new bifunctional click reagent for bioorthogonal conjugations: Application for DNA-Protein Cross-Linking.
Chemistry – A European Journal 21: 16091-16102, 2015.
Schiesser S., Hackner B., Vrábel M., Beck W., Carell T.:
Synthesis and DNA-Damaging Properties of Cisplatin-N-Mustard Conjugates.
European Journal of Organic Chemistry 2654-2660, 2015.
Ehrlich M., Gattner M.J., Viverge B., Bretzler J., Eisen D., Stadlmeier M., Vrábel M., Carell T.:
Orchestrating the biosynthesis of an unnatural pyrrolysine amino Acid for its direct incorporation into proteins inside living cells.
Chemistry - A European Journal 21: 7701-7704, 2015.
Gattner M.J., Ehrlich M., Vrabel M.:
Sulfonyl azide-mediated norbornene aziridination for orthogonal peptide and protein labeling.
Chemical Communications 50: 12568-12571, 2014.
Flügel V., Vrabel M., Schneider S.:
Structural basis for the site specific incorporation of lysine derivatives into proteins.
PLoS One 9: e96198, 2014.
Vrabel M., Kölle P., Brunner K.M., Gattner M.J., López-Carillo V., de Vivie-Riedle R., Carell T.:
Norbornenes in inverse electron-demand Diels-Alder reactions.
Chemistry - A European Journal 19: 13309-13312, 2013.
Schneider S., Gattner M.J., Vrabel M., Flügel V., López-Carrillo V., Prill S., Carell T.:
Structural Insights into Incorporation of Norbornene Amino Acids for Click Modification of Proteins.
ChemBioChem 14: 2114-2118, 2013.
Gattner M.J., Vrabel M., Carell T.:
Synthesis of ε-N-propionyl-, ε-N-butyryl-, and ε-N-crotonyl-lysine containing histone H3 using the pyrrolysine system.
Chemical Communications 49: 379-381, 2013.
Kaya E., Vrabel M., Deiml C., Prill S., Fluxa V.S., Carell T.:
Genetically encoded norbornene amino acid for the mild and selective modification of proteins in a copper-free click reaction.
Angewandte Chemie International Edition 51: 4466-4469, 2012.
Kaya E., Gutsmiedl K., Vrabel M., Mueller M., Thumbs P., Carell T.:
Synthesis of threefold glycosilated proteins using click chemistry and genetically encoded unnatural amino acids.
ChemBioChem 10: 2858-2861, 2009.