Chcete-li se dozvědět víc o možnostech PhD studia ve Fyziologickém ústavu, podrobnosti naleznete v sekci PhD program.
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Volné pozice
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Magisterské práce
Mitochondriální fyziologie
PhD Project:
Role of mitochondria in etiology of breast cancer
Metabolic pathways of cancer cells are often adjusted to produce energy and building material for cancer growth in order to provide clonal advantage over the normal cells. The pathways which ale very well characterized include…
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Biomatematika
PhD project 1:
Alteration of plasma membrane protein and lipid composition by oxidative stress; studies of rat brain and model cell lines …
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Bioenergetika
PhD project1:
Characterisation of TMEM70 protein function in mammalian mitochondria.
Our team was involved in the description and subsequent characterisation of TMEM70 protein acting as assembly factor for ATP synthase. Using mouse model of inducible TMEM70 knockout and cellular knockout models…
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Strukturní biologie signálních proteinů
PhD project:
Molecular mechanisms of 14-3-3 proteins in signaling complexes
14-3-3 proteins have the ability of binding the functionally different signal proteins, including kinases, phosphatases and transmembrane receptors by changing their function. Through the…
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Biologie tukové tkáně
PhD project: Complex screening of gene expression using RNA sequencing analysis with the focus on the early human development
Early postnatal period is critical with respect to development of the key physiological functions and homeostatic mechanisms of the newborn, as well as for imprinting the…
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Analýza fyziologicky aktivních látek
PhD Project1:
Influence of proteins and peptides in the protection against tooth caries
About 90% worldwide adults suffer from dental caries on enamel and root surfaces. The resistance of the lucky rest of population (10%) against the development of dental caries remains unclear. Dental caries…
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Molekulární neurobiologie
PhD project:
Collapsin response mediator proteins in neurodevelopmental disorders
Precise regulation of neural development is essential for normal function of the adult nervous system. Defects in neuron migration, branching or growth have been linked to several…
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Neurochemie
PhD project1:
Molecular mechanisms of signalling bias at muscarinic receptors.
Muscarinic acetylcholine receptors are G-protein coupled receptors (GPCRs) located in the plasma membrane of many cell types of various tissues. These receptors mediate extracellular to intracellular signalling.…
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Membránový transport
PhD project:
Structure and function of proteins participating in the homeostasis of alkali metal cations and intracellular pH
Ion homeostasis is a crucial requirement for all cells. They have developed efficient transport systems to acquire and store the desired elements and robust…
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Funkční morfologie
Department: Functional Morphology
http://www.fgu.cas.cz/departments/funkcni-morfologie
Research Summary: The main research interest of our department is to study mechanisms of pain and to explore new possibilities of pain treatment, especially in chronic states. Our…
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Buněčná neurofyziologie
PhD Project1:
Neurosteroid modulation of NMDA receptors
N-methyl-D-aspartate (NMDA) receptors are a type of ionotropic glutamate receptors mediating fast synaptic transmission and essential for learning and memory. Abnormal function of NMDA receptors underlies many neurological and…
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Buněčná a molekulární neuroendokrinologie
PhD project:
Molecular physiology of P2X receptors and their role in regulation of neuroendocrine cell function
The P2X receptors are ligand gated ion channels activated by extracellular ATP. They play a role in neurotransmission, modulation of neurotransmitter and hormone release,…
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Funkční morfologie
Na našem oddělení je možné vypracovat bakalářské, diplomové a doktorské práce na různá témata týkající se mechanizmů a vzniku bolestivých stavů.
Periferní a centrální mechanizmy bolestivých stavů
Modulace nocicepce na míšní úrovni
Úloha synaptické modulace při nociceptivním přenosu na míšní…
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