2004

Brynda J., Řezáčová P., Fábry M., Hořejší M., Šťouračová R., Souček M., Hradílek M., Konvalinka J., Sedláček J.:
Inhibitor binding at the protein interface in crystals of a HIV-1 protease complex.
Acta Crystallographica Section D: Biological Crystallography 11 (60): 1943-1948, 2004.

Petroková H., Dušková J., Dohnálek J., Skálová T., Vondráčková-Buchtelová E., Souček M., Konvalinka J., Brynda J., Fábry M., Sedláček J., Hašek J.:
Role of hydroxyl group and R/S configuration of isostere in binding properties of HIV-1 protease inhibitors.
European Journal of Biochemistry 22 (271): 4451-4461, 2004.

Švec M., Bauerová H., Pichova I., Konvalinka J., Stříšovský K.:
Proteinases of betaretroviruses bind single-stranded nucleic acids through a novel interaction module, the G-patch.
FEBS Letters 1-2 (576): 271-276, 2004.

Hlaváček J., Mařík J., Konvalinka J., Bennettová B., Tykva R.:
Synthesis and application of methyleneoxy pseudodipeptide building blocks in biologically active peptides.
Amino Acids 1 (27): 19-27, 2004.

Bařinka C., Mlčochová P., Šácha P., Hilgert I., Majer P., Slusher B.S., Hořejší V., Konvalinka J.:
Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding.
European Journal of Biochemistry 13 (271): 2782-2790, 2004.

Bařinka C., Šácha P., Sklenář J., Man P., Bezouška K., Slusher B.S., Konvalinka J.:
Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity.
Protein Science 6 (13): 1627-1635, 2004.

Brynda J., Řezáčová P., Fábry M., Hořejší M., Šťouračová R., Sedláček J., Souček M., Hradílek M., Lepšík M., Konvalinka J.:
A Phenylnorstatine Inhibitor Binding to HIV-1 Protease: Geometry, Protonation, and Subsite-Pocket Interactions Analyzed at Atomic Resolution.
Journal of Medicinal Chemistry 8 (47): 2030-2036, 2004.

Kožíšek M., Prejdová J., Souček M., Machala L., Staňková M., Linka M., Brůčková M., Konvalinka J.:
Characterisation of mutated proteinases derived from HIV-positive patients: Enzyme activity, vitality and inhibition.
Collection of Czechoslovak Chemical Communications 3 (69): 703-714, 2004.

Prejdová J., Souček M., Konvalinka J.:
Determining and overcoming resistance to HIV protease inhibitors.
Current Drug Targets - Infectious Disorders 2 (4): 137-152, 2004.