Coating of Ti39%Nb substrates by ferroelectric BaTiO₃ promotes the bone cell growth

We proved that ferroelectric immersed in a liquid influences electric charge distribution at the surface. Therefore ferroelectric coating on bone implant surface promotes bone cell growth and proliferation, healing should be improved [1].

We synthesized ferroelectric BaTiO₃ films on Ti and Ti39%Nb substrates by hydrothermal method [2, 3]. The bone cell growth is significantly higher on Ti39%Nb substrates coated by BaTiO₃ than that on non-coated Ti39%Nb, glass and reference polystyrene [3].

References
[1] P. Vaněk, Z. Kolská, T. Luxbacher, J.A.L. García, M. Lehocký, M. Vandrovcová, L. Bačáková, and J. Petzelt, Electrical activity of ferroelectric biomaterials and its effects on the adhesion, growth and enzymatic activity of human osteoblast-like cells, J. Phys. D: Appl. Phys. 49, 175403 (2016),
[2] P. Vaněk et al., Biocompatible ferroelectric coatings for bone implants, oral presentation at ISAF/ECAPD/PFM conference, Darmstadt, (2016),
[3] P. Vaněk, M. Vandrovcová et al., to be published.