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Education |
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2008 |
Ph.D., Department of Analytic Chemistry, Institute of Chemical Technology in Prague, Czech Republic; Thesis: Novel Approaches to Analysis and Resistance of HIV Protease. Supervisor: Prof. Vladimír Král. |
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2001 |
MSc., Department of Inorganic Chemistry, Faculty of Science, Charles University in Prague; Diploma thesis: Synthesis and Properties of 1,4,7-Tris(carboxymethyl)-10-phosphonomethyl-1,4,7,10-tetraazacyclododecane and its lanthanide complexes. Supervisor: Prof. Ivan Lukeš. |
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Experience |
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2007 |
Laboratoire de Chimie Organo-Minérale, Université Louis Pasteur, Strasburg, France (Professor Jean-Pierre Sauvage), 2 months, organometallic synthesis. |
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2004-2005 |
Department of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, Germany (Professor Vladimir Mirsky), 6 months, development of biosensors for detection of HIV protease resistance. |
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Appointments |
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since 2013 |
Head of the junior scientific team, Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Prague. |
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2009-2012 |
Scientist in team of Dr. M. Ledvina, Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Prague. |
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2008-2009 |
The Scripps Research Institute, La Jolla, U.S.A., postdoc (group of Prof. M. G. Finn). |
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2005-2008 |
Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Prague, research assistant (group of Dr. Jan Konvalinka: Proteases of human pathogens). |
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Awards and Fellowhisps |
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2008 |
Unipetrol Prize for thesis “Novel Approaches to Analysis and Resistance of HIV Protease”. |
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2006 |
Sanofi-Aventis Prize for Pharmacy (under the auspices of Professor Jean-Marie Lehn). |
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2005 |
Sholarship from Fellowship of International Quality Network – Medicinal Chemistry (IQN-MC), University of Regensburg. |
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2004 |
Erasmus Scholarship (Regensburg). |
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2004 |
Preciosa Scholarship. |
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2003-2004 |
Scholarship of Josef Hlávka Foundation. |
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2002-2004 |
Votoček’s Scholarship (Institute of Chemical Technology in Prague). |
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1996 |
Expo for Young Scientists (international competition), gold medal (Pretoria, Republic of South Africa). |
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1996 |
Talent '95 – The award of the Minister of Education, Youth, and Sports of the Czech Republic. |
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Research interest |
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Functional protein and inorganic nanoparticles. Their preparation and surface modifications. Construction of nanosensors and bionanosensors for recognition and determination of biologically interesting analytes. Multimodal in vivo analysis. Self-assembly and aggregation of molecules; molecular recognition. Design and synthesis of enzyme inhibitors. Exoskeletaly substituted carboranes and metallacarboranes; oligopyrrole macrocycles, azacrowns and their complexes. |
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Educational Activities and Popularization: |
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Member of Presidium of Czech Chemistry Olympiad; permanent author of competition tasks and reviewer (since 2000)
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Mentor a head mentor of Czech delegations at International Chemistry Olympiad (2006, 2008)
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Head of laboratories and lector at Summer school for young chemists in Bestvina (yearly, since 1998)
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Author of popularization articles on chemistry (e.g., co-author of 24-article serial in ABC journal: Unraveling the mystery of chemistry)
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