PHD PROGRAMME 2019 - CALL FOR APPLICATION (24.1. 2019)

The applícant must complete an on-line application form. More details  

The perspectíve PhD candidates will be contacted by the end of Apríl 2019

Ondřej Kuda získal Prémii Lumina quaeruntur (18.1. 2019)

Akademie věd ČR rozjíždí velkorysý program dotací pro úspěšné vědce a vědkyně mladší a střední generace s mezinárodními zkušenostmi. Prémie Lumina quaeruntur finančně podpoří perspektivní badatele, kteří si můžou sestavit svůj vlastní výzkumný tým na dobu až pěti let. Akademie věd představila program i jeho prvních šest laureátů na slavnostním ceremoniálu na Národní třídě ve čtvrtek 17. ledna.

Prvními nositeli stipendia je šest vědců z různorodých oborů, přičemž šanci mají i zahraniční vědci, kteří působí v rámci Akademie věd ČR. Mezi oceněnými je i Ondřej Kuda, specialista na metabolismus bioaktivních lipidů, který úzce souvisí s výzkumem cukrovky 2. typu.

Úplná zpráva

Alignment of mother and offspring body clock could prevent diseases such as heart disease and obesity (9.1. 2019)

The scientists from the Institute of Physiology CAS found out that the care provided by a mother can impact the body clock and health of offspring after birth. By reducing abnormalities in the body clock of offspring, it may be possible to develop therapies for serious lifestyle-related diseases, such as heart disease and obesity.

The body has an internal clock that regulates sleepiness over a 24 hour period, called your circadian rhythm. The circadian system is important so that processes in our body are synchronised with day and night, i.e. when it is light or dark outside. Disturbances in these mechanisms can lead to poor health, such as heart disease.

The mother-offspring interaction is very important for health later in adulthood. This is the first study to provide compelling evidence that the circadian characteristics of a mother may positively affect the likelihood of disease developing in offspring. Providing better maternal care significantly reduced abnormalities in the circadian system and resulted in a lower likelihood of development of heart disease.

The study conducted by the Institute of Physiology of the Czech Academy of Sciences was performed in two strains of laboratory rats, in which the maternal care and synchrony of their circadian clocks with external day/night cycle differed. The effect of maternal care provided by the genetic mother of these pups was compared with maternal care of the foster mother. The pups either had an aberrant circadian system and were genetically determined to develop disease in adulthood or they were healthy controls. The researchers tested the effect of maternal care on the body clock before and just after weaning, and on their activity rhythms, heart rate and blood pressure in adulthood. Proper maternal care provided to pups genetically predisposed to develop disease led to improvement of their clock function and abolished the rise in their heart rate in adulthood.

The data obtained in pups before weaning were based on population samples because the researchers could not assess circadian rhythms of the clocks in each individual pup within the body without disturbing maternal behaviour. Additionally, in the rat strain spontaneously developing disease, the molecular mechanisms connecting the circadian clock and the pathology is not understood.

These results point to a real possibility to reduce abnormalities in the offspring’s body clock and therefore limit the progression of disease in order to improve health. The future research will be directed at understanding in more detail how an aberrant circadian system contributes to the progression of disease. This research is worth future explorations as it may provide novel therapies for serious life-style related diseases in humans.

Olejníková, Lucie - Polidarová, Lenka - Behuliak, Michal - Sládek, Martin - Sumová, Alena: Circadian alignment in a foster mother improves the offspring's pathological phenotype.  Journal of Physiology. Roč. 596, č. 23 (2018), s. 5757-5775. ISSN 0022-3751, IF: 4.540, 2017.

IPHYS CAS applies for HR Award (8.1. 2019)

The Institute of Physiology of the Czech Academy of Sciences endorses the principles of The European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers and has begun the HRS4R implementation process. The Institute has conducted a GAP analysis of  the HR environment and prepared an action plan based on the analysis. The GAP analysis, action plan and all supporting documents have been submitted for review by the European Commission on December the 7th 2018, have been formally accepted and are currently in the review process.

Tchajwan delegation is interested in the topic of biomaterials and tissue engineering (5.12. 2018)

Akademie věd ČR navázala spolupraci s vědeckými pracovišti na Tchaj-wanu v roce 2017, kdy bylo podepsáno memorandum s Průmyslově-technologickým výzkumným institutem (Industrial Technology Research Institute – ITRI). Úkolem nové platformy je podpořit konkrétní spolupráce mezi ústavy Akademie věd ČR a ITRI.

Ve dnech 19. až 21. listopadu 2018 proběhla návštěva tchajwanské delegace v Akademii věd ČR, kdy se mj. také uskutečnil seminář, kterému předcházela exkurze do výzkumných center ELI Beamlines v Dolních Břežanech a BIOCEV ve Vestci. V rámci semináře vystoupila také Markéta Bačáková, která představila výzkum biomateriálů a tkáňového inženýrství a využití strukturní biologie při navrhování nových léčiv. Tato témata tchajwanskou delegaci velmi zaujala a obě strany se shodly na tématech, jež by rády dále rozpracovaly do konkrétních projektů. Celá zpráva