Research

Seizure Onset Zone localization and advanced analysis of high-frequency intracranial EEG

Epilepsy is one of the most prevalent neurological diseases. One-third of patients has to undergo an invasive surgical resection of epileptogenic tissue. To achieve seizure freedom in these patients, the localization of epileptogenic tissue is crucial. Currently used localization methods are not utilizing computational power and advanced signal processing techniques, which are now available and has the potential to improve the invasive treatment of epilepsy substantially.

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Interdisciplinary Collaboration in Metrology with Cold Quantum Objects and Fibre Networks

We present the project of creating a partner network - intersectoral cooperation network between research organizations and industry with a focus on the development of quantum technologies in the Czech Republic. The project will launch a joint research in metrology with cold quantum objects, focusing on applications for new photonic services, and it will also contribute to increase the competitiveness of Czech industry in the field of telecommunication and photonics.

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Dynamic impact test as a method of analyses of mechanical properties of protective coatings used in industry

The aim of this project is a dynamic impact analysis of a protective coatings. This unique method can be used to evaluation of an impact resistance and impact wear of the protective coatings used in a wide range of industry sectors, such as a mechanical engineering, automotive industry or energetics. Nowadays, there are only two institutes in Europe with research and development focused on thy dynamic impact test – Aristotle University in Thessaloniki and Institute of Scientific Instruments, CAS (ISI). For dynamical impact testing can be used tester developed on ISI.

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Biological role of polyhydroxyalkanoates in cyanobacteria

Cyanobacteria are ubiquitous Gram-negative prokaryotes capable of performing oxygenic photosynthesis. These microbes are extremely environmentally important since they are crucial players in oxygen generation and CO2 and N2 fixation on the Earth. Furthermore, cyanobacteria are also employed in biotechnology. Numerous cyanobacteria, similarly as many non-photosynthesizing prokaryotes, accumulate polyhydroxyalkanoates (PHA), polyesters which serve primarily as storage materials.

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Multidimensional nonlinear optomechanics of levitated nanosystems

Optomechanics of levitating objects is building its theoretical and experimental foundations in interaction of photons and mechanical states of an object levitating in vacuum. This concept is unique in (i) tunability of key parameters of the optical trap in individual axes leading to desired non-linearity and dimensionality, (ii) relatively massive object oscillating with low friction and interacting with a thermal bath with tunable temperature and (iii) decreasing energy of the object and bringing it closer to the basic quantum state.

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Directed evolution of polyhydroxyalkanoates producing bacteria

Polyhydroxyalkanoates (PHAs) are polyesters which are accumulated in form of intracellular inclusions by numerous prokaryotes. These materials primarily serve as carbon and energy storage; nevertheless, their biological function is far more complex. Generally, presence of PHAs in microbial cells enhances their robustness against various stress factors. Apart from their biological function, PHAs attract attention as ecological alternative to petrochemical plastics which can be biotechnologically produced from waste streams of various industrial processes.

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Coherently programmable source of nonclassical light

The nonclassical light is an essential resource in almost all areas of rapidly developing applications of quantum information research. As previously demonstrated, individual trapped atomic ions can constitute a scalable source of nonclassical light with record-breaking purity. Furthermore, unprecedent spatial localization of many ions allows employing optical coherence for manipulation of the emitted fluorescence direction. In this project, a source of nonclassical light allowing combination of these two unique properties will be realized for the first time.

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Advanced simulations of electron-gas interactions for high-efficiency detection of secondary electrons under dynamic in-situ experiments in ESEM.

Based on knowledge in the field of physics of electron-gas interactions and simulations of these phenomena, our MC software for ESEM will be adapted to a higher speed and accuracy of simulations, especially thanks to an optimised algorithm and the possibility to direct integration of precise gas flow data. The data will be counted using the enhanced mathematical model for ANSYS Fluent software, realized in the project. Simulation results will be tested in the design of a new differentially pumped part of the ESEM objective and high-efficiency detection systems.

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The Spectroscopy and Microscopy of Chemical Compounds in Ice within the Environmental and Pharmaceutical Domains

Ice is a scantily explored reaction medium that catalyzes a large number of processes and reactions; some of these, such as bromine explosion and the related ozone layer depletion, have a major impact on the natural environment. Ice in nature hosts many compounds; however, neither their location on ice nor the chemical identity have been sufficiently explained thus far, despite being of essential importance for the compounds' (photo)reactivity. In this project we will examine the compounds' behaviour via optical spectroscopies and environmental electron microscopy.

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Ecological epoxy casting systems for electrical engineering applications

Strategy of the further development of SYNPO, a.s. is to gain a competitive advantage in the market in the area of sophisticated development of casting systems by cooperation with the academic partner and to expand own production of prefilled casting systems for electrotechnical industry. Four new prefilled casting systems will be developed (3 for indoor, 1 for outdoor use) with hardeners complying with authorization REACH, one prospectively based on ecological resin EnviPOXY.

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