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Education |
1979-1983 |
CSc. (Ph.D.), Biochemistry, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague. |
1969-1974 |
Ing. (M.Sc.), Chemistry, Institute of Chemical Technology, Prague. |
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Experience |
1990-1992 |
Postdoctoral research associate, Department of Physiology, University of Florida, U.S.A., Prof. M. K. Raizada. |
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Appointments |
since 2013 |
Scientist, targeted research team Antiobesity peptides, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague. |
2007-2012 |
Scientist, Jiracek's group, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague. |
1985-2006 |
Scientist, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague. |
1974-1978 |
Research Assistant, Institute of Chemical Technology, Prague. |
1978-9, 1983-5, 1986-9 |
Maternity leave. |
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Research interest |
- Structure-activity studies of peptides (cholecystokinin analogues, CART peptides) with special emphasis on their anorectic activity after central and peripheral administration; binding affinities, in vitro and in vivo functional assays.
- Study of food intake regulation in mouse models of obesity.
- Ligand binding and signal transduction in cultured cells (study of LDL receptor, putative CART receptor in neuronal cell cultures).
- Effect of leptin and ghrelin on development of experimental arthritis. Ligand binding and signal transduction in cultured cells (study of LDL receptor, putative CART receptor in neuronal cell cultures).
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