Optical Biosensors

Focus

The team is engaged in the research of photonic and plasmonic (nano) structures and functional biomolecular files, the development of optical measuring methods and systems, the study of biomolecular interactions and detection of chemical and biological agents in areas such as medical diagnostics, food quality control or environmental monitoring.

Research projects

• ULTRAsensitive PLAsmonic devices for early CAncer Diagnosis (ULTRAPLACAD)
• Interactions of intracellular amyloid beta and diagnosis of Alzheimer disease
• Nanobiophotonics for future health care (project of excellence)

Complete overview of research projects

Publications

1. H. Lísalová, E. Brynda, M. Houska, I. Víšová, K. Mrkvová, X. Chadtová Song, E. Gedeonová, F. Surman, T. Riedel, O. Pop-Georgievski, and J. Homola: Ultralow-Fouling Behavior of Biorecognition Coatings Based on Carboxy-Functional Brushes of Zwitterionic Homo- and Copolymers in Blood Plasma: Functionalization Matters, Analytical Chemistry,89, 3524-3531 (2017).
2. T. Špringer, X. Chadtová Song, M. L. Ermini, J. Lamačová, J. Homola: Functional gold nanoparticles for optical affinity biosensing, Analytical and Bioanalytical Chemistry, 409, 4087–4097 (2017).
3. M. Kalousová, S. Dusilová-Sulková, A. Kuběna, O. Zakiyanov, K Levová, M. Bocková, E. Gedeonová, X. Chadtová Song, M. L. Ermini, T. Špringer, J. Homola, V. Tesař, and T. Zima: Pregnancy-associated plasma protein A2 in hemodialysis patients: significance for prognosis, Kidney and Blood Pressure Research, 42, 509-518 (2017).
4. N. S. Lynn Jr., J. Homola: (Bio)sensing using nanoparticle arrays: on the effect of analyte transport on sensitivity, Analytical Chemistry, 88, 12145–12151 (2016).
5. B. Špačková, P. Wrobel, M. Bocková, J. Homola: Optical biosensors based on plasmonic nanostructures: a review, Proceedings of the IEEE, 104, 2380–2408 (2016).

Complete overview of publications