Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and the Institute of Experimental Botany of the Czech Academy of Sciences (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Workers
head of the laboratorysenior scientist
- doc. Mgr. Ondřej Novák Ph.D.
senior scientist
scientist
- RNDr. Martin Fellner Ph.D.
- Jiří Grúz
- Doc., Ing. Jan Krekule DrSc.
- Doc. RNDr. Vladimír Kryštof Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- Mgr. Marie Kvasnicová
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Jiří Pospíšil
- Jitka Široká
- Prof. ing. Miroslav Strnad CSc.
- Mgr. Danuše Tarkowská Ph.D.
- Jiří Voller
scientific assistant
- Michaela Mrvková
- Mgr. Lukáš Spíchal Ph.D.
graduated technical assistant
assistant
- Jitka Hansgutová DiS.
postdoc
- Mgr. Martina Kopečná PhD.
- Aleš Pěnčík
- Lenka Plačková
- Marek Szecówka PhD
- Terezie Urbanová
postgraduate student
maintenance
Research projects
Publications
2021
- MOLECULAR PLANT 2021 (External fulltext)
-
Synthesis and Biological Activity of Brassinosteroid Analogues with a Nitrogen-Containing Side ChainINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 155 2021
- BIOMOLECULES 11 27 2021
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 2021
2020
- FOOD AND CHEMICAL TOXICOLOGY 137 2020
- FRONTIERS IN PLANT SCIENCE 11 736 2020 (External fulltext)
- PLANTS 9 1325 2020 (External fulltext)
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21 7266 2020 (External fulltext)
- MICROORGANISMS Microorganisms 8 1005 2020 (External fulltext)
- MOLECULES 25 3274 2020 (External fulltext)