People

Name Železná Blanka
Position Scientist
Dr. Blanka Železná

Blanka Železná, Ph.D.

Scientist


Antiobesity peptides
Institute of Organic Chemistry and Biochemistry of the CAS
Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

☎: (+420) 220 183 345

 
Education
1979-1983 CSc. (Ph.D.), Biochemistry, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague.
1969-1974 Ing. (M.Sc.), Chemistry, Institute of Chemical Technology, Prague.
 
Experience
1990-1992 Postdoctoral research associate, Department of Physiology, University of Florida, U.S.A., Prof. M. K. Raizada.
 
Appointments
since 2013 Scientist, targeted research team Antiobesity peptides, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague.
2007-2012 Scientist, Jiracek's group, Institute of Organic Chemistry and Biochemistry v.v.i., Academy of Sciences of the Czech Republic, Prague.
1985-2006 Scientist, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague.
1974-1978 Research Assistant, Institute of Chemical Technology, Prague.
1978-9, 1983-5, 1986-9 Maternity leave.
 
Research interest
  • Structure-activity studies of peptides (cholecystokinin analogues, CART peptides) with special emphasis on their anorectic activity after central and peripheral administration; binding affinities, in vitro and in vivo functional assays.
  • Study of food intake regulation in mouse models of obesity.
  • Ligand binding and signal transduction in cultured cells (study of LDL receptor, putative CART receptor in neuronal cell cultures).
  • Effect of leptin and ghrelin on development of experimental arthritis. Ligand binding and signal transduction in cultured cells (study of LDL receptor, putative CART receptor in neuronal cell cultures).