Projects
Tetrafluoroethyl and tetrafluoroethylene group transfer
Starting from dibromotetrafluoroethane we have synthesized a variety of nucleophilic and radical sulfur-containing compounds, which are now under investigation as reagents for tetrafluoroethyl and tetrafluoroethylene group transfer...
The chemistry of polyfluorinated azides
In 2017, we reported a breakthrough in azide chemistry. CF3N3 and longer carbon chain analogues were prepared from silanes or other carbanion precursors, which opened a door to study properties and reactivity of these compounds...
New methodologies for the preparation of (pentafluorosulfanyl)benzenes
Organic compounds with pentafluorosulfanyl (SF5) groups display a unique set of physicochemical properties. This includes extreme kinetic and hydrolytic stability, very strong electron acceptor capability, and high lipophilicity with high SF5 electronegativity...
Chemistry of fluorinated phosphonates
We have developed new methodologies for nucleophilic transfer of fluorine-containing groups using fluorinated phosphonates...
Properties of perfluorocarbon solvents
In this project we exploit extremely inert and hydrophobic properties of perfluorinated hydrocarbons by employing them as reaction media in enzyme-catalyzed processes. We perform biocatalysis (using isolated enzymes or whole cells) in perfluorocarbons...
Synthesis and modifications of plant growth regulators
In 2004, germination promotor of many plant species worldwide has been isolated from the smoke of burning vegetation. This remarkable potent germination stimulant, with effective germination promotion observed at nanomolar concentrations (10-9M) was identified independently by Flematti and Van Staden...