The rationale of Energy-X is to develop the science as well as technology enabling a sustainable production of synthetic fuels for energy storage and as feedstock for the chemical and materials industry. Energy-X brings together interdisciplinary academic research (chemistry, physics, engineering and economic science) with cross-industrial technological expertise (chemical, engineering, utilities, mobility, agriculture) to provide a platform for future chemical energy conversion technology in Europe. Energy-X will contribute disruptive new science and technology enabling efficient conversion of solar and wind energy into chemical form and will combine this ambition with scale-up to industrially relevant conditions by integrating with European industry. Energy-X will also transfer the knowledge into two demonstration projects: manufacturing of carbon-neutral aviation fuels and decentralized production of fertilizers with no CO2 footprint.