Selection Procedures
Institute of Organic Chemistry and Biochemistry of the CAS in accordance with the Act No. 283/1992 of the Academy of Sciences of the Czech Republic, as amended by the Act No. 420/2005, and in accordance with the Statutes of the Academy of Sciences of the Czech Republic, invites applications for a POSTDOCTORAL POSITION IN BIOORGANIC CHEMISTRY.
Postdoctoral position in bioorganic chemistry
Jiří Jiráček Group is seeking a highly motivated individual who is willing to accept the challenge of cutting-edge research in the development of peptide hormone mimetics.
Job description:
This multidisciplinary research program combines molecular modeling-aided combinatorial chemical synthesis of peptide hormone mimetics with their biological and structural characterization. The successful applicant for this postdoc position will be an outstanding, self-driven person who will explore the organic synthesis and solid-phase synthesis of peptidomimetics as well as biological characterization of compounds.
We offer:
We offer a competitive salary financed by the European Regional Development Fund and a stable position lasting one to three years and starting on 1 January 2020. Located in the stunning city of Prague, our research facilities feature a state-of-the-art instrumentation portfolio.
Requirements:
Applicants must have a Ph.D. in synthetic organic chemistry or a closely related discipline. Candidates must be the first author of at least two publications. The position requires prior experience in synthetic organic chemistry. Experience in biological testing of compounds is a definite plus. Excellent oral and written communication skills in English are required, as is the ability to conduct independent scientific investigations. The position is being offered for 12 months starting from 1 January 2020 and will likely be extended.
How to apply:
Please send cover letter, CV, and contact information for two or three references in a single PDF file to Jiří Jiráček, Ph.D.: jiri.jiracek@uochb.cas.cz.
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences / IOCB Prague (www.uochb.cz) is a leading internationally recognized scientific institution whose primary mission is the pursuit of basic research in chemical biology and medicinal chemistry, organic and materials chemistry, chemistry of natural substances, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. An integral part of the IOCB Prague’s mission is the implementation of the results of basic research in practice. Emphasis on interdisciplinary research gives rise to a wide range of applications in medicine, pharmacy, and other fields.
Deadline: 18. 12. 2019
The Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic opens a position in the Department of Functional Morphology in the group of Jiri Palecek M.D. Ph.D. for a:
POSTDOCTORAL POSITION IN PAIN RESEARCH
The postdoctoral position is available for 3 years with a possible extension as a junior scientist.
The main research interest of the department is to study mechanisms of pain and to explore new possibilities of pain treatment, especially in chronic states. Our experimental work is concentrated on the modulation of nociceptive information at the spinal cord level that is the first relay center between the periphery and the higher brain areas. The goal is to study these modulatory mechanisms in order to improve therapy for neuropathic and cancer related pain. In our research we use mainly electrophysiological, immunohistochemical and behavioral methods with the employment of different models of neuropathic (nerve injury, diabetes) and inflammatory pain models in control and transgenic animals. We have recently also established a new laboratory at the Biotechnology and Biomedicine Center (www.biocev.eu). More information about the department profile is available at: http://www.fgu.cas.cz/en/departments/functional-morphology
Annotation of the research project
The research project will concentrate to study mechanisms of spinal cord modulation of nociceptive transmission in models of neuropathic pain. The postdoctoral fellow will use electrophysiological recordings from spinal cord slices, behavioral tests and molecular biology techniques. Experience with these methods and with viral transfection in vivo for optogenetic manipulation of synaptic transmission and siRNA approaches for targeted inactivation of genes of interest would be of advantage. The postdoctoral fellow will be involved in projects to study interaction of opioid, TRPV1 and cannabinoid receptors with cytokines in modulation of synaptic transmission in different models of neuropathic pain (SNL, paclitaxel, diabetic). Possible anti-inflammatory and pro-resolving properties of fatty acids will be also studied in neuroinflammatory conditions related to neuropathic pain. Viral vectors will be used to label neuronal populations with calcium dye indicators and to record their activity in spinal cord slices using optical and electrophysiological methods in the BIOCEV facility.
We therefore seek for this position a highly motivated candidate with a PhD degree interested to study pain mechanisms, fluent in English (or Czech). Previous experience with the experimental techniques and/or pain field is of advantage.
We offer a competitive monthly salary of 40 000 CZK (approx. 1 500 EUR) with a possible raise based on the candidate's skills and involvement in grant projects. For further information please contact Jiri Palecek (jiri.palecek@fgu.cas.cz). The position is open from 1.1.2020.
To apply, please, send letter of interest, structured CV, list of publications, photocopies of documents proving the attained level of education, and recommendation letters of two independent academic referees to the following address: marcela.tomaskova@fgu.cas.cz
Applications need to be received by December 15th 2019. Institute of Physiology, Czech Academy of Sciences, Videnska 1083, 142 20 - Prague 4, Czech Republic.
By replying to this advertisement (or by sending a CV), the job seeker acknowledges that, in connection with the ongoing selection procedure for a particular job position, the Institute of Physiology of the Academy of Sciences of the Czech Republic, v.v.i., is processing personal data.
Mandatory information related to the processing of personal data is available at www.fgu.cas.cz
Deadline: 15. 12. 2019
Job Description for a researcher – postdoc at Research Centre of Cosmic Rays and Radiation Events in the Atmosphere
The CRREAT team performs measurements of the atmospheric radiation and ionization events on satellites, aircraft, unmanned aerial vehicles, monitoring cars, and ground stations. The CRREAT project (www.crreat.eu) shall contribute to the improvement of space weather models, air transport safety, and global navigation systems reliability.
Objectives of the project CRREAT are to deepen the knowledge about the relation between atmospheric phenomena and ionizing radiation, and to clarify phenomena causing variations of the secondary cosmic particles (SCP) in the atmosphere.
Job description
The main work of the candidate consists of the evaluation of the data received from our measurement devices used in the atmospheric studies and to build up a database that allows us to easily investigate relationships between the different data sets and allow easy access of other scientists and the public. The tasks comprise:
- Analysis of the basic requirements for the treatment of large and complex data sets
- Development of software for data management and its technical application
- Participation in measurement campaigns
- Contribution towards optimization of existing radiation measurement systems and design of novel systems
- Preparation of scientific papers and presentations at international conferences
- Preparation of grant applications
- Supervision work of undergraduate and graduate students
- Close cooperation with research institutes from France, Germany, Slovakia, Armenia, Russia, USA, and Japan
Requirements:
- Doctoral degree in Physics or Applied Mathematics or related fields
- Experience in data analysis
- Autonomous familiarization in new technologies and scientific domains
- Ability to work in a team
- Very good knowledge of English language (written and oral)
- Ability to present results at scientific and technical meetings
We offer:
- The opportunity to participate in the international scientific project
- Competitive and motivating salary
- Career growth
- 5 weeks of vacation, lunch vouchers, support of leisure activities
Please send your CV, recommendation, and motivation letter to Dr. Günther Reitz (Guenther.Reitz@dlr.de), copy to Ondrej Ploc (ploc@ujf.cas.cz), and Josef Šalamon (salamon@ujf.cas.cz). The workplace is located in Prague 8, Czech Republic, at the Department of Radiation Dosimetry of Nuclear Physics Institute of the CAS v. v. i. The expected date of commencement is January 1st, 2020, but it can be also before this date. The duration of the job position is almost three years (until the end of October 2022).
The Institute of Photonics and Electronics v. v. i., in accordance with the Act No. 283/1992 of the Academy of Sciences of the Czech Republic, as amended by the Act No. 420/2005, and in accordance with the Statutes of the Academy of Sciences of the Czech Republic, invites applications for a Postdoctoral Research Fellow position in the field of Photonics for Biosensing.
Responsibilities and tasks
The selected candidate will carry out research into optical methods and measurement systems for plasmonic biosensors. Specifically, the selected candidate will be expected to develop advanced optical platforms based on plasmonic (nano)structures for affinity biosensing and participate in their applications for the detection of biomolecules and investigation of biomolecular interactions related to medical diagnostics.
Requirements
- Ph.D. degree in optics, optoelectronics, physics, electrical engineering or similar,
- publication record in the field of optical measurement methods, optical systems, waveguide optics and/or plasmonics, and optical (bio)sensing,
- experience in the design and experimental development of advanced optical platforms.
We offer
- interesting and challenging job in an international environment,
- work in a vibrant and multidisciplinary research team
- excellent research infrastructure,
- full time employment with 5 weeks of vacation and other benefits (flexible working hours, sport, catering and pension contribution)
Terms of employment
The initial period of employment is 1 year (with the possibility of an extension), starting from January 1, 2020 or as soon as possible thereafter.
Application procedure
In order to apply, please, send a letter of application (cover letter), CV, and a list of publications to Ms. Jana Petrlova (petrlova@ufe.cz).
In the subject line of your email, please, state that you apply for Postdoctoral Research Fellow Position in Photonics for Biosensing.