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Recent papers

Enzymatic Preparation of 2′–5′,3′–5′-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations
Barbora Novotná
Lenka Vaneková
Martin Zavřel
Miloš Buděšínský
Milan Dejmek
Miroslav Smola
Ondrej Gutten
Zahra Aliakbar Tehrani
Markéta Pimková Polidarová
Andrea Brázdová
Radek Liboska
Ivan Štěpánek
Zdeněk Vavřina
Tomáš Jandušík
Radim Nencka
Lubomír Rulíšek
Evžen Bouřa
Jiří Brynda
Ondřej Páv
Gabriel Birkuš
Journal of Medicinal Chemistry 62 (23): 10676-10690 (2019).
No magnesium is needed for binding of the stimulator of interferon genes to cyclic dinucleotides
Miroslav Smola
Gabriel Birkuš
Evžen Bouřa
Acta Crystallographica Section F: Structural Biology Communications 75 (9): 593-598 (2019).
Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs
O. Barauskas
W. Xing
E. Aguayo
M. Willkom
A. Sapre
M. Clarke
Gabriel Birkuš
B. E. Schultz
R. Sakowicz
H. J. Kwon
J. Y. Feng
PLOS ONE 12 (10): e0185998 (2017).
Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors
W. Xing
O. Barauskas
T. Kirschberg
A. Niedziela-Majka
M. Clarke
Gabriel Birkuš
P. Weissburg
X. Liu
B. E. Schultz
R. Sakowicz
H. J. Kwon
J. Y. Feng
PLOS ONE 12 (8): e0181969 (2017).