Institute of Molecular Genetics of the Czech Academy of Sciences (IMG) is a public research institution, an important part of the Czech Academy of Sciences. It focuses on research in the fields of molecular and cell biology, immunology, genomics and bioinformatics.

	Genetics, Genomics and Bioinformatics Research focused on development of new genetic models (mice, chicken, fish), clarification of genetic factors associated with various diseases, sequencing and analysis of large parts of the genome and large volumes of genomic data.
	Molecular Virology The main topic of this research field are cell receptors, which allow viruses to enter into the cell, and retroviruses, which are able to incorporate themselves into the host genome and alter it.
	Molecular Oncology Research of oncogenes and anti-oncogenes, activation mechanisms of these genes in cells, shifts in chromosomes, and the role of other factors that are responsible for oncogenic transformation of cells.
	Cell Biology and Immunology Cell biology research is focused on the molecular structure of the cytoskeleton (microtubules), molecular architecture of the cell nucleus and its role in transcription and regulation of genes. Immunology research is focused on the molecular mechanisms responsible for activation of various types of white blood cells and the role of membrane microdomains and several signalling molecules.
	Cell Signaling Molecular mechanisms of signal transduction from cell receptors to the inner parts of the cell leading to cell activation, proliferation, apoptosis, or secretion of specific products.

The main priority of the Institute activity lies in basic research with publications in prestigious international journals as its main output, but also valuable applied research with particular practical applications. An essential contributor to this goal are service groups and state-of-the-art large national research infrastructures
(Czech-Bioimaging, Czech Centre for Phenogenomics and CZ-OPENSCREEN), which ensure optimal usage of sophisticated instruments and provide a basis for development of new tools and methods utilized by the scientific community not only at IMG, but also at other institutes and research laboratories in the Czech Republic or abroad.