Selection Procedures
The Institute of Biotechnology of the Czech Academy of Sciences announces in accordance with the Act No. 283/1992 Coll. on the Czech Academy of Sciences, and the Statutes of the Czech Academy of Sciences a position
Ph.D. studentin the Laboratory of structure and function of biomolecules
(PI Jan Dohnalek)
The Ph.D. student position is in a project focused on structure-function studies of bacterial transcription systems.
Requirements:
- University education (biochemistry, structural biology, genetics, molecular and cell biology, bioinformatics or related fields)
- Practical experience in recombinant protein expression or in structural biology is an advantage
- Good communication and organizational skills
- Readiness for high workload
- Good level of English, spoken and written
Project activities:
- Recombinant expression and purification of components of bacterial transcription system and of newly identified interacting partners
- Characterization of formation of protein-protein complexes with use of biophysical methods
- Structure analysis of complexes and of individual proteins
- Data analysis and interpretation
Starting date: immediately/can be negotiated
Send you written applications including motivation letter, brief professional CV and references to: jan.dohnalek@ibt.cas.cz.
Information about the Laboratory:
http://www.ibt.cas.cz/vyzkum/laboratore/laborator-struktury-a-funkce-biomolekul/index.html
or
https://sites.google.com/site/pragueprotein/
Application deadline: June 30, 2020
We hereby inform you that the Institute of Biotechnology of the Czech Academy of Sciences shall process your personal data only to the extent for the purposes of selection of a suitable employee and closure of a contract of employment in accordance with the General Data Protection Regulation 2016/679 (GDPR).
More details on the processing of personal data of an applicant for open position are available at web site: http://www.ibt.cas.cz/o-ustavu/GDPR.html.
IMG & IPHYS Proteomics Facility
CAS – Biomedical Research Campus in Prague – Krč
The newly established Proteomics Facility on the Biomedical Research Campus in Prague, Czech Republic, is seeking an MSc or PhD level scientist with expertise in LC-MS for a position:
Proteomics Facility LC-MS Operator
Position Requirements:
- MSc or PhD in biochemistry / chemistry / biology or related field
- Experience in running and troubleshooting HPLC and mass spectrometer
- Experience in method design for HPLC and/or mass spectrometer
- Experience in sample preparation and method development for proteomics valued but not required
- Strong communication skills, solid command of English, proficiency with PC
Responsibilities:
- Operate and maintain HPLC + mass spectrometer (nano UHPLC + HRAM Q-Orbitrap / Q-TOF)
- Prepare proteomics samples from tissues, cells, and biofluids
- Optimize and develop sample preparation and acquisition methods
- Analyze and report proteomics data to the clients of the facility
We Offer:
- Work with the latest technologies
- Collaborative academic environment
- Competitive salary and benefits
Expected Appointment Start Date: September 2020
Required Documents:
- Cover Letter
- Resume
to be sent by the applicant to the contact below by July 12, 2020
Contact:
Marcela Tomášková
marcela.tomaskova@fgu.cas.cz
The Institute of Photonics and Electronics v. v. i. in accordance with the Act No.283/1992 of the Academy of Sciences of the Czech Republic, as amended by the Act No. 420/2005, and in accordance with the Statute of the Academy of Sciences of the Czech Republic, announces an open position for postdoctoral research fellow or scientist.
Electromagnetics scientist / postdoc position in Bioelectrodynamics research team
Do you want to work on exciting projects at the interface of nanotechnology and electromagnetics? Do you love microwave technology and micro/nanofabrication technologies? Then apply for this position!
Job description:
At the Bioelectrodynamics research team (Institute of Photonics and Electronics of the Czech Academy of Sciences), we are looking for a highly motivated researcher for leveraging advanced electromagnetics approaches (bandgap, metamaterial, topological, etc.) in bionanotechnology. To that end, you will design, fabricate and characterize microfluidic microwave and subTHz chip and planar devices. Your chips will be the corner stones of cutting-edge experiments to verify the predictions of the molecular dynamics simulations of your colleagues. This position is offered within the project funded by national excellent fundamental research program EXPRO. The grand goal of the project is to probe and control biological components (protein nanostructures) using ultrashort microwave and subTHz pulses. Your results will contribute to the development of novel electromagnetic technologies for gentler and more effective biomedicine and bionanotechnology of the future.
Requirements:
- Ph.D. in applied physics, electromagnetic physics, electrical, electromagnetic, radio-frequency engineering, high-frequency electronics, or similar
- Very good communication skills and the ability to work in a team-focused environment.
We offer:
The Czech Academy of Sciences is internationally highly ranked research institution with exceptional quality growth. At the Institute of Photonics and Electronics of CAS, we offer interesting and challenging job in an international environment, work in a multidisciplinary research team and excellent research infrastructure. We ensure a strong support of career growth towards professional and scientific independence.
Above that we offer:
- 5 weeks of vacation + 3 sick days benefit
- Flexible working hours
- Annual performance bonus
- Friendly team of supporting colleagues
- Modern educational courses and trainings for continuous professional and scientific development
- Sport allowance - MultiSport card, catering and pension contribution, team building events, fully automatic coffee machine in the team
Application procedure
Please apply through the application link and instructions therein.
Deadline for application: 31st May 2020
Starting date of the position: as soon as possible
In order to conduct the selection procedure on the position you are applying for it is necessary to collect and process your personal data. By replying to this ad, you provide to the Institute of Photonics and Electronics, Czech Academy of Sciences (located at Chaberská 57, 18251, Praha 8, Czech Republic) your personal data only for the purpose of the selection process. The personal data shall be stored for the duration of the selection procedure, and further for max. 6 months after the termination of the selection procedure for the legitimate interest of the controller in order to prove the proper course of the selection procedure and to evaluate the results of the selection procedure. During metioned period personal data can be stored on our internal and an external storage (owned by Microsoft Corp.) with dedicated access. After the above period expires, your personal data will be permanently deleted.
Job Description
A chemist position in Targeted research group HBV Cure (head Gabriel Birkuš, Ph.D.) is available for a highly motivated and creative scientist with expertise in organic chemistry. The project is focused on the identification of novel cGAS inhibitors.
GMP-AMP synthase (cGAS) serves as a sensor of cytosolic dsDNA and plays an essential role in innate immunity against viral/bacterial infection and cellular damage. Upon binding of dsDNA, cGAS synthesizes a cyclic dinucleotide 2’3’cGAMP that serves as a second messenger and initiates an inflammatory cellular response. Uncontrolled activation of the cGAS pathway has been implicated in autoimmune and autoinflammatory diseases such as Aicardi-Goutieres syndrome or Systemic Lupus Erythematosus. Thus, inhibition of cGAS may be of therapeutic benefit in some diseases.
The successful candidate will be a member of a multidisciplinary team and be involved in our efforts to identify novel cGAS inhibitors. He or she will be responsible for the synthesis of target compounds. The candidate will also have a unique opportunity to experience the lead optimization process of drug development. An attractive salary and an opportunity to work with clinical candidates guaranteed.
Requirements
The applicant must have an M.Sc. degree in organic chemistry. We are looking for independent applicants with basic knowledge of synthetic organic chemistry and standard purification techniques. Good oral and written communication skills in English are required.
We offer
- 5 weeks holiday
- 3 sick-days
- meal allowance
- contribution to supplementary pension savings
- other employee benefits
The position is available starting from now.
Please submit your resume, motivation letter, and contact information by e-mail to Ondřej Páv, Ph.D. at ondrej.pav@uochb.cas.cz
---
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences / IOCB Prague is a leading internationally recognized scientific institution whose primary mission is the pursuit of basic research in chemical biology and medicinal chemistry, organic and materials chemistry, chemistry of natural substances, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. An integral part of the IOCB Prague’s mission is the implementation of the results of basic research in practice. Emphasis on interdisciplinary research gives rise to a wide range of applications in medicine, pharmacy, and other fields.
Institute of Organic Chemistry and Biochemistry of the CAS / IOCB Prague
Flemingovo n. 542/2
166 10 Prague 6
Czech Republic
Job Description
A postdoctoral position in Targeted research group HBV Cure (head Gabriel Birkuš, Ph.D.) is available for a highly motivated and creative scientist with expertise in organic chemistry. The project is focused on the identification of novel cGAS inhibitors.
GMP-AMP synthase (cGAS) serves as a sensor of cytosolic dsDNA and plays an essential role in innate immunity against viral/bacterial infection and cellular damage. Upon binding of dsDNA, cGAS synthesizes a cyclic dinucleotide 2’3’cGAMP that serves as a second messenger and initiates an inflammatory cellular response. Uncontrolled activation of the cGAS pathway has been implicated in autoimmune and autoinflammatory diseases such as Aicardi-Goutieres syndrome or Systemic Lupus Erythematosus. Thus, inhibition of cGAS may be of therapeutic benefit in some diseases.
The successful candidate will be a member of a multidisciplinary team and be involved in our efforts to identify novel cGAS inhibitors. He or she will be responsible for the synthesis of target compounds. The candidate will also have a unique opportunity to experience the lead optimization process of drug development. An attractive salary and an opportunity to work with clinical candidates guaranteed.
Requirements
The applicant must have a Ph.D. in organic chemistry. We are looking for independent thinkers with excellent expertise in synthetic organic chemistry, and with knowledge of analytical and spectroscopic methods. Experience in medicinal chemistry is an advantage. Good oral and written communication skills in English are required.
We offer
- 5 weeks holiday
- 3 sick-days
- meal allowance
- contribution to supplementary pension savings
- other employee benefits
The position is available starting from now.
Please submit your resume, motivation letter, and contact information by e-mail to Ondřej Páv, Ph.D. at ondrej.pav@uochb.cas.cz.
---
The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences / IOCB Prague is a leading internationally recognized scientific institution whose primary mission is the pursuit of basic research in chemical biology and medicinal chemistry, organic and materials chemistry, chemistry of natural substances, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. An integral part of the IOCB Prague’s mission is the implementation of the results of basic research in practice. Emphasis on interdisciplinary research gives rise to a wide range of applications in medicine, pharmacy, and other fields.
Institute of Organic Chemistry and Biochemistry of the CAS / IOCB Prague
Flemingovo n. 542/2
166 10 Prague 6
Czech Republic