Laboratoř růstových regulátorů
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and Institute of Experimental Botany, Academy of Sciences of the Czech Republic (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Pracovníci
vedoucí skupinyvedoucí vědecký pracovník
- doc. Mgr. Ondřej Novák Ph.D.
vedoucí vědecký pracovník
vědecký pracovník
- RNDr. Martin Fellner Ph.D.
- Jiří Grúz
- Doc., Ing. Jan Krekule DrSc.
- Doc. RNDr. Vladimír Kryštof Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- Mgr. Marie Kvasnicová
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Jiří Pospíšil
- Jitka Široká
- Prof. ing. Miroslav Strnad CSc.
- Mgr. Danuše Tarkowská Ph.D.
- Jiří Voller
vědecký asistent
- Michaela Mrvková
- Mgr. Lukáš Spíchal Ph.D.
odborný pracovník
sekretářka-asistentka
- Jitka Hansgutová DiS.
postdoktorand
- Mgr. Martina Kopečná PhD.
- Aleš Pěnčík
- Lenka Plačková
- Marek Szecówka PhD
- Terezie Urbanová
doktorand
údržba
Výzkumné projekty
- Biosyntéza a signalizace u giberelinů - identifikace nových cílů pro regulaci růstu rostlin , GA ČR , Peter Hedden
- Syntéza nových brassinosteroidů a studium jejich interakce s rostlinnými a živočišnými receptory , GA ČR , Miroslav Kvasnica
- Cílené metabolické profilování rostlinných růstových regulátorů , MŠMT , Ondřej Novák
Publikace
2015
- PLoS ONE 10 (2) e0117793 2015 (External fulltext)
- BMC GENOMICS 16 878- 893 2015 (External fulltext)
- PLANT GENOME 8 1-13 2015 (External fulltext)
- PLANT SIGNALLING & BEHAVIOR 10: 8 e1039213 2015 (External fulltext)
- PLoS ONE 10 (4) e0121864 2015 (External fulltext)
2014
- MEDIATORS OF INFLAMMATION 2014 1-8 2014
- PNAS 2014 E3571-E3580 2014
- NATURE COMMUNICATIONS 1-12 2014 Fulltext: veřejný PDF odkaz (External fulltext)
- BOTANY / BOTANIQUE 92 332-339 2014
2013
- NATURAL PRODUCT COMMUNICATIONS 8 105-108 2013