Jiří Brynda

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Latest publications

Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors

R. Reiberger K. Radilová M. Král V. Zima P. Majer J. Brynda M. Dračínský J. Konvalinka M. Kožíšek A. Machara

International Journal of Molecular Sciences 22 (14): 7735 (2021)

Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery

R. Kryštůfek P. Šácha J. Starková J. Brynda M. Hradilek E. Tloušťová J. Grzymska W. Rut M. J. Boucher M. Drag P. Majer M. Hájek P. Řezáčová H. D. Madhani C. S. Craik J. Konvalinka

Journal of Medicinal Chemistry 64 (10): 6706–6719 (2021)

Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors

A. Jílková P. Rubešová J. Fanfrlík P. Fajtová P. Řezáčová J. Brynda M. Lepšík H. Mertlíková-Kaiserová C. D. Emal A. R. Renslo W. R. Roush M. Horn C. R. Caffrey M. Mareš

ACS Infectious Diseases 7 (5): 1077–1088 (2021)

Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds

M. Kugler J. Nekvinda J. Holub S. El Anwar V. Das V. Šícha K. Pospíšilová M. Fábry J. Brynda V. Kašička P. Řezáčová M. Hajdúch B. Grüner

ChemBioChem 2021: Early View