Imaging and data analysis

ALISI is prepared to optimize the measurement and data processing protocols for answering specific questions and to carry out the necessary measurements. Due to the complexity of the technology and the enormous flexibility of NMR measurements, collaborative work may be the most suitable way to maximizing the synergy between the core competence of the client and the NMR competence of the ALISI teams.

MR imaging, localized spectroscopy and spectroscopic imaging

• Spatial mapping of 2D slices or 3D volumes, spatial resolution down to about 0.1×0.1×1 mm³ (10 nL) now, 0.05×0.05×1 mm³ (2.5 nL) as of 2011.
• Images weighted by spin density, T1, T2, T2*, diffusion, magnetic susceptibility.
• Molecule-specific images (water, fat, specific small molecules).
• Quantitative imaging of relaxation, diffusion, perfusion, flow, temperature changes, magnetic susceptibility.
• Mapping of the 3D spatial distribution of selected small molecules, particularly for in vivo studies of cell cultures, plants, extracted tissues, small animals (mouse, rat – as of 2011).
• Quantization of metabolite ratios in vivo.

MR data analysis

• MR imaging and spectroscopic imaging: own software Marevisi (developed in cooperation with National Research Council Canada – Institute for Biodiagnostics) – processing and visualization of multidimensional MR data sets.
• MR spectroscopic imaging: quantum-mechanics based simulations and data processing, software jMRUI (developed in collaboration by a consortium of European research institutions).
• Customized MR data analysis solutions.
• Evaluation of perfusion studies.

Education and training

• Customized courses, demonstrations and system-operation training available to pre- or postgraduate university programs or research-oriented professionals.