We are enhancing our
understanding
of the genetic basis for
human diseases

What can we help you with

Microinjection

Model Generation

Genetically modified rodent models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. 
Phenotyping

Phenotyping

The genomes of humans, mice and other species have been completely sequenced, yet the knowledge of genome sequences as such does not shed light on questions concerning the functions of these sequences. 

Animal Facility

The Animal Facility Module of the Czech Center for Phenogenomics is based on the latest advances in housing, breeding and care of laboratory mice and rats. 
Mouse tumors

Preclinical Testing

The Czech Centre for Phenogenomics can offer a very broad portfolio of highly standardized assays useful for preclinical studies on rodents including established disease models. 

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Latest News

27. 12. 2021

Season’s greetings and the best wishes for the New Year

We wish you all the best for the New Year and look forward to cooperating with you in 2022.

13. 12. 2021

CCP evaluated in the International peer-review of large research infrastructures in the Czech Republic in 2021

In the first half of 2021, the Ministry of Education, Youth and Sports organized an international peer-review of large research infrastructures in the Czech Republic, which results were published in December. The purpose of this evaluation was to obtain independent expert reviews about the performance of large research infrastructures. CCP confirmed its top level. According…

10. 12. 2021

Infrafrontier in the new ESFRI 2021 Roadmap

The updated ESFRI Roadmap was published this week. INFRAFRONTIER is mentioned as an example of ESFRI Research Infrastructures in response to emergencies, specifically to the covid-19 crisis. “INFRAFRONTIER rapidly evolved a broad portfolio of services to evaluate the potential of new anti-COVID-19 compounds and therapeutics on suitable humanized models as well as BSL3 laboratories for…

About Czech Centre for Phenogenomics

Genetically modified mouse models have become a key tool in basic and biomedical research. The ability to engineer the mouse genome has greatly transformed biomedical research in the last decade. Crucial for this technology is the ability to control the expression of genes of interest. It is possible to increase or decrease gene expression, or eliminate the expression of a gene completely.

Transgenic and gene knockout/knockin technologies have become important experimental tools for assigning functions to genes at the level of whole complexity of organism, creating models of genetic disorders, evaluating effects drugs and toxins, thus helping to answer fundamental issues in basic and applied research.