Laboratoř růstových regulátorů
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and Institute of Experimental Botany, Academy of Sciences of the Czech Republic (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Pracovníci
vedoucí skupinyvedoucí vědecký pracovník
- doc. Mgr. Ondřej Novák Ph.D.
vedoucí vědecký pracovník
vědecký pracovník
- RNDr. Martin Fellner Ph.D.
- Jiří Grúz
- Doc., Ing. Jan Krekule DrSc.
- Doc. RNDr. Vladimír Kryštof Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- Mgr. Marie Kvasnicová
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Jiří Pospíšil
- Jitka Široká
- Prof. ing. Miroslav Strnad CSc.
- Mgr. Danuše Tarkowská Ph.D.
- Jiří Voller
vědecký asistent
- Michaela Mrvková
- Mgr. Lukáš Spíchal Ph.D.
odborný pracovník
sekretářka-asistentka
- Jitka Hansgutová DiS.
postdoktorand
- Mgr. Martina Kopečná PhD.
- Aleš Pěnčík
- Lenka Plačková
- Marek Szecówka PhD
- Terezie Urbanová
doktorand
údržba
Výzkumné projekty
- Biosyntéza a signalizace u giberelinů - identifikace nových cílů pro regulaci růstu rostlin , GA ČR , Peter Hedden
- Syntéza nových brassinosteroidů a studium jejich interakce s rostlinnými a živočišnými receptory , GA ČR , Miroslav Kvasnica
- Cílené metabolické profilování rostlinných růstových regulátorů , MŠMT , Ondřej Novák
Publikace
2018
- JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 178 263-271 2018
- JOURNAL OF NATURAL PRODUCTS 81(11) 2321-2328 2018
- FRONTIERS IN PLANT SCIENCE 9 655 2018
2017
-
Microscale magnetic microparticle-based immunopurification of cytokinins from Arabidopsis root apex.PLANT JOURNAL 85 1065-1075 2017
- PHYTOCHEMISTRY 135 115-127 2017
- PLANT PHYSIOLOGY 173 552-565 2017 (External fulltext)
- ANNALS OF BOTANY 119 151-166 2017 Fulltext: PDF link pouze na intranetu
- ANNUAL REVIEW OF PLANT BIOLOGY 68 323-348 2017
- NATURE COMMUNICATIONS 8 14752 2017
- PLoS ONE 12 e0170715 2017 (External fulltext)