Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and the Institute of Experimental Botany of the Czech Academy of Sciences (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Workers
head of the laboratorysenior scientist
- doc. Mgr. Ondřej Novák Ph.D.
senior scientist
scientist
- RNDr. Martin Fellner Ph.D.
- Jiří Grúz
- Doc., Ing. Jan Krekule DrSc.
- Doc. RNDr. Vladimír Kryštof Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- Mgr. Marie Kvasnicová
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Jiří Pospíšil
- Jitka Široká
- Prof. ing. Miroslav Strnad CSc.
- Mgr. Danuše Tarkowská Ph.D.
- Jiří Voller
scientific assistant
- Michaela Mrvková
- Mgr. Lukáš Spíchal Ph.D.
graduated technical assistant
assistant
- Jitka Hansgutová DiS.
postdoc
- Mgr. Martina Kopečná PhD.
- Aleš Pěnčík
- Lenka Plačková
- Marek Szecówka PhD
- Terezie Urbanová
postgraduate student
maintenance
Research projects
Publications
2022
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 4618 2022 (External fulltext)
- PLANTS 11 618 2022 (External fulltext)
- PLANT CELL AND ENVIRONMENT 45 1315-1332 2022 (External fulltext)
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 4618 2022 (External fulltext)
- DEVELOPMENTAL CELL 2022 (External fulltext)
- PLANTS 11 313 2022 (External fulltext)
- PROCEEDINGS OF THE NAS OF THE USA 119 e2000482119 2022 (External fulltext)
- FRONTIERS IN PLANT SCIENCE 13 804716 2022 (External fulltext)
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 2936 2022 (External fulltext)
- FRONTIERS IN PLANT SCIENCE 13 844292 2022 (External fulltext)