Laboratory of Plant Biotechnologies

RNDr. Marcela Dvořáková, Ph.D.

Born: 19.05.1981 in Prague

Education:

2005 - 2013 Postgraduate Doctoral Course at Charles University in Prague, Faculty of Science, Department of Organic Chemistry
Ph.D. thesis entitled: The synthesis of stable O-acetyl-adenosine diphosphoribose analogs and inhibitors of sirtuins
Qualification degree: Ph.D.

1999 - 2005 Charles University, Prague, Faculty of Science, Department of Organic Chemistry
Diploma thesis entitled: Biotransformation of monoterpenic mixtures by in vitro cultures of higher plants.
Qualification degree: M.Sc.


Professional experiences:

from 2013 Institute of Experimental Botany AS CR, Prague Laboratory of Plant Biotechnologies
Position: postdoc
Work activity: synthesis of paclitaxel derivatives with the aim to improve paclitaxel´s water solubility and cytotoxic activity, and to prepare derivatives for the targeted therapy

2007 - 2013 Institute of Experimental Botany AS CR, Prague Laboratory of Plant Biotechnologies
Position: Ph.D. student
Work activity: synthesis of paclitaxel derivatives with the aim to improve paclitaxel´s water solubility and cytotoxic activity, and to prepare derivatives for the targeted therapy

2007 – 2008 Queen’s University Belfast, School of Chemistry and Chemical Engineering, United Kingdom (Marie Curie Fellowship)
Position: Postgraduate Research Trainee
Work activity: The synthesis of stable O-acetyl-ADPR analogs and inhibitors of Sir2 enzymes

2005 - 2006 Institute of Organic Chemistry and Biochemistry AS CR, Prague Department of Plant Tissue Cultures
Position: research worker
Work activity: synthesis of paclitaxel derivatives with the aim to improve paclitaxel´s water solubility and cytotoxic activity, and to prepare derivatives for the targeted therapy

2003 - 2005 Institute of Organic Chemistry and Biochemistry AS CR, Prague Department of Plant Tissue Cultures
Position: diploma student
Work activity: The study of biotransformation of monoterpenic mixtures by in vitro cultures of higher plants

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