Publications

Novohradsky V., Markova L., Kostrhunova H., Kasparkova J., Hoeschele J., Brabec V. (2022), A [Pt(cis-1,3-diaminocycloalkane)Cl2] analog exhibits hallmarks typical of immunogenic cell death inducers in model cancer cells., Journal of Inorganic Biochemistry

Švecová E., Ostatná V., Fojt L., Hermannová M., Velebný V., Ondreáš F. (2022), Adsorption/desorption behavior of hyaluronic acid fragments at charged hydrophobic surface, Carbohydrate Polymers

Bohálová N., Dobrovolná M., Brázda V., Bidula S. (2022), Conservation and over-representation of G-quadruplex sequences in regulatory regions of mitochondrial DNA across distinct taxonomic sub-groups, Biochimie

Casas-luna M., Montufar E.B., Hort N., Díaz-de-la-torre S., Méndez-garcía J.C., Vištejnová L., Brínek A., Danhel A., Dvorak K., Kaiser J., Celko L. (2022), Degradable magnesium-hydroxyapatite interpenetrating phase composites processed by current assisted metal infiltration in additive-manufactured porous preforms, Journal of Magnesium and Alloys

Malina J., Kostrhunova H., Brabec V. (2022), Dinuclear nickel(II) supramolecular helicates down-regulate gene expression in human cells by stabilizing DNA G-quadruplexes formed in the promoter regions, Inorganic Chemistry Frontiers

Markova L., Novohradsky V., Kasparkova J., Ruiz J., Brabec V. (2022), Dipyridophenazine iridium(III) complex as a phototoxic cancer stem cell selective, mitochondria targeting agent, Chemico-Biological Interactions

Soňa Legartová, Alena Svobodová Kovaříková, Jana Běhalová Suchánková, Hana Polášek-Sedláčková and Eva Bártová (2022), Early recruitment of PARP-dependent m8A RNA methylation at DNA lesions is subsequently accompanied by active DNA demethylation, RNA Biology

Fojt L., Grüner B., Nekvinda J., Tűzűn E.Z., Havran L., Fojta M. (2022), Electrochemistry of Cobalta Bis(dicarbollide) Ions Substituted at Carbon Atoms with Hydrophilic Alkylhydroxy and Carboxy Groups, Molecules

Fojt L., Grüner B., Holub J., Havran L., Fojta M. (2022), Electrochemistry of Icosahedral Metal Full and Half Sandwich Metallacarboranes in Phosphate Buffers, Journal of Electroanalytical Chemistry

Havran L., Vacek J., Dorčák V. (2022), Free and bound histidine in reactions at mercury electrode, Journal of Electroanalytical Chemistry

Cantara A., Luo Y., Dobrovolná M., Bohalova N., Fojta M., Verga D., Guittat L., Cucchiarini A., Savrimoutou S., Häberli C., Guillon J., Keiser J., Brázda V., Mergny J.L. (2022), G-quadruplexes in helminth parasites, Nucleic Acids Research

Hreusova M., Novohradsky V., Markova L., Kostrhunova H., Potočňák I., Brabec V., Kasparkova J. (2022), Gallium(III) complex with cloxyquin ligands induces ferroptosis in cancer cells and is a potent agent against both differentiated and tumorigenic cancer stem Rhabdomyosarcoma cells, Bioinorganic Chemistry and Applications

Holoubek J., Bednářová K., Haviernik J., Huvarová I., Dvořáková Z., Černý J., Outlá M., Salát J., Konkol'ová E., Boura E., Růžek D., Vorlíčková M., Eyer L., Renčiuk D. (2022), Guanine quadruplexes in the RNA genome of the tick-borne encephalitis virus: their role as a new antiviral target and in virus biology, Nucleic Acids Research, 50, 4574 - 4600

Legartová S, Fagherazzi P, Goswami P, Brazda V, Lochmanová G, Koutná I, Bártová E (2022), Irradiation potentiates p53 phosphorylation and p53 binding to the promoter and coding region of the TP53 gene, Biochimie

Kasparkova J., Kostrhunova H., Novohradsky V., Ma L., Zhu G., Milaeva E. R., Shtill A. A., Vinck R., Gasser G., Brabec V., Nazarov A. A. (2022), Is antitumor Pt(IV) complex containing two axial lonidamine ligands a true dual- or multi-action prodrug?, Metallomics

Malina J., Kostrhunova H., Novohradsky V., Scott P., Brabec V. (2022), Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles., Nucleic Acids Research

Brázda V., Bohálová N., Bowater R.P. (2022), New telomere to telomere assembly of human chromosome 8 reveals a previous underestimation of G-quadruplex forming sequences and inverted repeats, Genes

Kasparkova J., Kostrhunova H., Novohradsky V., Logvinov A. A., Temnov V. V., Borisova N. E., Podrugina T. A., Markova L., Starha P., Nazarov A. A., Brabec V. (2022), Novel cis-Pt(II) complexes with alkylpyrazole ligands: Synthesis, characterization, and unusual mode of anticancer action, Bioinorganic Chemistry and Applications

Novohradsky V., Markova L., Kostrhunova H., Svitelova M., Kasparkova J., Barbanente A., Papadia P., Margiotta N., Hoeschele J. D., Brabec V. (2022), Pt(II) complex containing the 1R,2R enantiomer of trans-1,2-diamino-4-cyclohexene ligand effectively and selectively inhibits the viability of aggressive pancreatic adenocarcinoma cells and alters their lipid metabolism, Inorganic Chemistry Frontiers

Cervinka J., Gobbo A., Biancalana L., Markova L., Novohradsky V., Guelfi M., Zacchini S., Kasparkova J., Brabec V., Marchetti F. (2022), Ruthenium(II)–tris-pyrazolylmethane complexes inhibit cancer cell growth by disrupting mitochondrial calcium homeostasis, Journal of Medicinal Chemistry

Bartas M., Slychko K., Brázda V., Červeň J., Beaudoin Ch.A., Blundell T.L., Pečinka P. (2022), Searching for New Z-DNA/Z-RNA Binding Proteins Based on Structural Similarity to Experimentally Validated Zα Domain, International Journal of Molecular Sciences

El Anwar S., Pazderová L., Bavol D., Bakardjiev M., Růžičková Z., Horáček O., Fojt L., Kučera R., Grűner B. (2022), Structurally rigidified cobalt bis(dicarbollide) derivatives, a chiral platform for labelling of biomolecules and new materials, Chemical Communications

Legartová S, Lochmanová G, Bártová E (2022), The Highest Density of Phosphorylated Histone H1 Appeared in Prophase and Prometaphase in Parallel with Reduced H3K9me3, and HDAC1 Depletion Increased H1.2/H1.3 and H1.4 Serine 38 Phosphorylation, Life (Basel)

(2022), Variation in G-quadruplex sequence and topology differentially impacts human DNA polymerase fidelity,

MaryElizabeth Stein, Suzanne E. Hile, Matthias H. Weissensteiner, Marietta Lee, Sufang Zhang, Eduard Kejnovský, Iva Kejnovská, Kateryna D. Makova, Kristin A. Eckert (2022), Variation in G-quadruplex sequence and topology differentially impacts human DNA polymerase fidelity, DNA Repair, 119, 103402