Laboratory of Integrative Structural Biology
The laboratory aims to understand how the wiring of different biomolecules drives fundamental processes of the plant cell, such as cytokinesis, cell-wall material secretion or nutrient uptake. We employ a multidisciplinary strategy combining experimental and computational approaches to achieve this goal. We utilise methods of molecular biology, biochemistry and state-of-the-art microscopy. By combining the experimental techniques with the computational ones (structural bioinformatics, molecular dynamics) in an integrative fashion, we can obtain unprecedented details of a given process, leading to novel biological implications.
Keywords
Integrative Structural Biology, Structural Bioinformatics, Molecular Dynamics, Biochemistry, Microscopy, Cell Division, Callose Synthesis, Endocytosis, TPLATE complex, protein-membrane interfaces.
Workers
head of the laboratory
- Ing. Roman Pleskot Ph.D.
deputy head of the laboratorygraduated technical assistant
- Mgr. Roman Hudeček
graduated technical assistant
- Ing. Daniela Kocourková PhD.
- Ing. Tereza Podmanická
postgraduate student
Research projects
Publications
2014
- FRONTIERS IN PLANT SCIENCE 5 5 2014 (External fulltext)
- Plant Cell Morphogenesis: Methods and Protocols 1080 231-236 2014 (External fulltext)
- NEW PHYTOLOGIST 203 483-494 2014 (External fulltext)
- FRONTIERS IN PLANT SCIENCE 4 543 2014
2013
- PROGRESS IN LIPID RESEARCH 52 62-79 2013 (External fulltext)
- TRENDS IN PLANT SCIENCE 2013 (External fulltext)
2012
- FRONTIERS IN PLANT SCIENCE 3 54 2012 (External fulltext)
- PLOS COMPUTATIONAL BIOLOGY 8 e1002765 2012 (External fulltext)
- PLANT SIGNALLING & BEHAVIOR in press 2012
2011
- JOURNAL OF EXPERIMENTAL BOTANY 2011 (External fulltext)